Picrotin

Modify Date: 2024-01-03 13:48:34

Picrotin structure	Common Name	Picrotin
	CAS Number	21416-53-5	Molecular Weight	310.29900
	Density	1.59g/cm3	Boiling Point	595.8ºC at 760 mmHg
	Molecular Formula	C₁₅H₁₈O₇	Melting Point	256-258ºC
	MSDS	Chinese USA	Flash Point	228.9ºC

Use of Picrotin

Picrotin is an inhibitor of glycine receptors (GlyRs) which blocks α2 GlyR, α1 GlyR and α3 GlyR[1][2].

Name	picrotin
Synonym	More Synonyms

Description	Picrotin is an inhibitor of glycine receptors (GlyRs) which blocks α2 GlyR, α1 GlyR and α3 GlyR[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
Target	α2 GlyR, α1 GlyR, α3 GlyR[1][2]
References	[1]. Li P, et al. Gating effects on picrotin block of glycine receptors. Neuroreport. 2012 Dec 5;23(17):1017-20. [2]. Yang Z, et al. A proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore. J Neurochem. 2007 Oct;103(2):580-9.

Density	1.59g/cm3
Boiling Point	595.8ºC at 760 mmHg
Melting Point	256-258ºC
Molecular Formula	C₁₅H₁₈O₇
Molecular Weight	310.29900
Flash Point	228.9ºC
Exact Mass	310.10500
PSA	105.59000
Vapour Pressure	1.12E-16mmHg at 25°C
Index of Refraction	1.637

Picrotin MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TJ8800000

CHEMICAL NAME :: Picrotin

CAS REGISTRY NUMBER :: 21416-53-5

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C15-H18-O7

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,729,1968

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	TJ8800000

(1aR,2aR,3S,6R,6aS,8aS,8bR,9S)-Hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-3,6-methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione

picrotoxin component 2

(-)-Picrotin

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Picrotin
Price: ￥1088.0/10mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Picrotin
Price:
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Picrotin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Picrotin

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