BPK-29

Modify Date: 2025-08-25 18:35:00

BPK-29 Structure
BPK-29 structure
Common Name BPK-29
CAS Number 2143467-62-1 Molecular Weight 470.00
Density N/A Boiling Point N/A
Molecular Formula C26H32ClN3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BPK-29


BPK-29 is a covalent small molecule that disrupts NR0B1 complexes and impairs the anchorage-independent growth of KEAP1-mutant cancer cells[1].

 Names

Name BPK-29

 BPK-29 Biological Activity

Description BPK-29 is a covalent small molecule that disrupts NR0B1 complexes and impairs the anchorage-independent growth of KEAP1-mutant cancer cells[1].
Related Catalog
In Vitro BPK-29 substantially engages NR0B1 with good overall proteomic selectivity in KEAP1-mutant Non-Small Cell Lung Cancers[1].
References

[1]. Woodruff TM,et al. The complement factor C5a contributes to pathology in a rat model of amyotrophic lateral sclerosis. J Immunol. 2008 Dec 15;181(12):8727-34.

 Chemical & Physical Properties

Molecular Formula C26H32ClN3O3
Molecular Weight 470.00
InChIKey ZKWKNYRAPOSUDO-UHFFFAOYSA-N
SMILES O=C(c1ccc(N2CCOCC2)cc1)N1CCCC(N(Cc2ccccc2)C(=O)CCl)CC1
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