3-amino-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide

Modify Date: 2024-01-09 17:52:06

3-amino-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Structure
3-amino-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide structure
Common Name 3-amino-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide
CAS Number 214823-09-3 Molecular Weight 210.20500
Density N/A Boiling Point N/A
Molecular Formula C10H11FN2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 3-amino-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C10H11FN2O2
Molecular Weight 210.20500
Exact Mass 210.08000
PSA 79.33000
LogP 1.77130

 Synthetic Route

~59%

3-amino-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Structure

3-amino-8-fluor...

CAS#:214823-09-3

Literature: WYETH Patent: WO2005/12291 A1, 2005 ; Location in patent: Page/Page column 66 ; WO 2005/012291 A1

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3-amino-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Structure

3-amino-8-fluor...

CAS#:214823-09-3

Literature: Hatzenbuhler, Nicole T.; Evrard, Deborah A.; Harrison, Boyd L.; Huryn, Donna; Inghrim, Jennifer; Kraml, Christina; Mattes, James F.; Mewshaw, Richard E.; Zhou, Dahui; Hornby, Geoffrey; Lin, Qian; Smith, Deborah L.; Sullivan, Kelly M.; Schlechter, Lee E.; Beyer, Chad E.; Andree, Terrance H. Journal of Medicinal Chemistry, 2006 , vol. 49, # 15 p. 4785 - 4789

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3-amino-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Structure

3-amino-8-fluor...

CAS#:214823-09-3

Literature: Hatzenbuhler, Nicole T.; Evrard, Deborah A.; Harrison, Boyd L.; Huryn, Donna; Inghrim, Jennifer; Kraml, Christina; Mattes, James F.; Mewshaw, Richard E.; Zhou, Dahui; Hornby, Geoffrey; Lin, Qian; Smith, Deborah L.; Sullivan, Kelly M.; Schlechter, Lee E.; Beyer, Chad E.; Andree, Terrance H. Journal of Medicinal Chemistry, 2006 , vol. 49, # 15 p. 4785 - 4789

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3-amino-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Structure

3-amino-8-fluor...

CAS#:214823-09-3

Literature: Hatzenbuhler, Nicole T.; Evrard, Deborah A.; Harrison, Boyd L.; Huryn, Donna; Inghrim, Jennifer; Kraml, Christina; Mattes, James F.; Mewshaw, Richard E.; Zhou, Dahui; Hornby, Geoffrey; Lin, Qian; Smith, Deborah L.; Sullivan, Kelly M.; Schlechter, Lee E.; Beyer, Chad E.; Andree, Terrance H. Journal of Medicinal Chemistry, 2006 , vol. 49, # 15 p. 4785 - 4789

~%

3-amino-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Structure

3-amino-8-fluor...

CAS#:214823-09-3

Literature: Hatzenbuhler, Nicole T.; Evrard, Deborah A.; Harrison, Boyd L.; Huryn, Donna; Inghrim, Jennifer; Kraml, Christina; Mattes, James F.; Mewshaw, Richard E.; Zhou, Dahui; Hornby, Geoffrey; Lin, Qian; Smith, Deborah L.; Sullivan, Kelly M.; Schlechter, Lee E.; Beyer, Chad E.; Andree, Terrance H. Journal of Medicinal Chemistry, 2006 , vol. 49, # 15 p. 4785 - 4789

~%

3-amino-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Structure

3-amino-8-fluor...

CAS#:214823-09-3

Literature: Hatzenbuhler, Nicole T.; Evrard, Deborah A.; Harrison, Boyd L.; Huryn, Donna; Inghrim, Jennifer; Kraml, Christina; Mattes, James F.; Mewshaw, Richard E.; Zhou, Dahui; Hornby, Geoffrey; Lin, Qian; Smith, Deborah L.; Sullivan, Kelly M.; Schlechter, Lee E.; Beyer, Chad E.; Andree, Terrance H. Journal of Medicinal Chemistry, 2006 , vol. 49, # 15 p. 4785 - 4789

~%

3-amino-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Structure

3-amino-8-fluor...

CAS#:214823-09-3

Literature: Hatzenbuhler, Nicole T.; Evrard, Deborah A.; Harrison, Boyd L.; Huryn, Donna; Inghrim, Jennifer; Kraml, Christina; Mattes, James F.; Mewshaw, Richard E.; Zhou, Dahui; Hornby, Geoffrey; Lin, Qian; Smith, Deborah L.; Sullivan, Kelly M.; Schlechter, Lee E.; Beyer, Chad E.; Andree, Terrance H. Journal of Medicinal Chemistry, 2006 , vol. 49, # 15 p. 4785 - 4789

 Synonyms

3-amino-8-fluorochroman-5-carboxamide
3-amino-8-fluorochromane-5-carboxamide
2H-1-Benzopyran-5-carboxamide,3-amino-8-fluoro-3,4-dihydro
3-Amino-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide