Propargyl-PEG5-PFP ester

Modify Date: 2025-08-26 13:09:10

Propargyl-PEG5-PFP ester Structure
Propargyl-PEG5-PFP ester structure
Common Name Propargyl-PEG5-PFP ester
CAS Number 2148295-92-3 Molecular Weight 470.38
Density N/A Boiling Point N/A
Molecular Formula C20H23F5O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG5-PFP ester


Propargyl-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG5-PFP ester
Synonym More Synonyms

 Propargyl-PEG5-PFP ester Biological Activity

Description Propargyl-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C20H23F5O7
Molecular Weight 470.38

 Synonyms

MFCD29049371
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