DNP-PEG4-DBCO

Modify Date: 2024-04-02 11:25:50

DNP-PEG4-DBCO Structure
DNP-PEG4-DBCO structure
Common Name DNP-PEG4-DBCO
CAS Number 2149585-17-9 Molecular Weight 689.71
Density N/A Boiling Point N/A
Molecular Formula C35H39N5O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DNP-PEG4-DBCO


DNP-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DNP-PEG4-DBCO

 DNP-PEG4-DBCO Biological Activity

Description DNP-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C35H39N5O10
Molecular Weight 689.71
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