SIQ17

Modify Date: 2024-03-08 23:07:03

SIQ17 structure	Common Name	SIQ17
	CAS Number	2151881-74-0	Molecular Weight	489.63
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₂H₂₇NO₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SIQ17

SIQ17 is an EGFR inhibitor that inhibits its activity by occupying the ATP-binding site, with IC50 of 0.62 nM. SIQ17 shows more effective EGFR-TK inhibitory activity compared to the known inhibitor Erlotinib (HY-50896) (IC50 of ∼20 nM). SIQ17 can be used for cancer research[1]

Name	SIQ17

Description	SIQ17 is an EGFR inhibitor that inhibits its activity by occupying the ATP-binding site, with IC50 of 0.62 nM. SIQ17 shows more effective EGFR-TK inhibitory activity compared to the known inhibitor Erlotinib (HY-50896) (IC50 of ∼20 nM). SIQ17 can be used for cancer research[1]
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
References	[1]. Hengphasatporn K,et.al. Sulfonylated Indeno[1,2-c]quinoline Derivatives as Potent EGFR Tyrosine Kinase Inhibitors. ACS Omega. 2023 May 23;8(22):19645-19655.

Molecular Formula	C₃₂H₂₇NO₂S
Molecular Weight	489.63

SIQ17

Use of SIQ17

Names

SIQ17 Biological Activity

Chemical & Physical Properties