ONO-8711

Modify Date: 2024-01-08 09:20:19

ONO-8711 structure	Common Name	ONO-8711
	CAS Number	216158-34-8	Molecular Weight	439.996
	Density	1.3±0.1 g/cm3	Boiling Point	605.2±65.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₃₀ClNO₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	319.8±34.3 °C

Use of ONO-8711

ONO-8711 is a potent and selective competitive antagonist of EP1 receptor (Ki = 0.6 and 1.7 nM for human and mouse EP1 respectively). ONO-8711 effectively reduces tumor incidence and multiplicity in mouse models of colon, breast, and oral cancer[1].

Name	(Z)-6-[(2S,3R)-2-[[(4-chloro-2-methylphenyl)sulfonylamino]methyl]-3-bicyclo[2.2.2]octanyl]hex-5-enoic acid
Synonym	More Synonyms

Description	ONO-8711 is a potent and selective competitive antagonist of EP1 receptor (Ki = 0.6 and 1.7 nM for human and mouse EP1 respectively). ONO-8711 effectively reduces tumor incidence and multiplicity in mouse models of colon, breast, and oral cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
References	[1]. Watanabe K, et al. Role of the prostaglandin E receptor subtype EP1 in colon carcinogenesis. Cancer Res. 1999 Oct 15;59(20):5093-6.

Density	1.3±0.1 g/cm3
Boiling Point	605.2±65.0 °C at 760 mmHg
Molecular Formula	C₂₂H₃₀ClNO₄S
Molecular Weight	439.996
Flash Point	319.8±34.3 °C
Exact Mass	439.158417
PSA	91.85000
LogP	6.01
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.580

(5Z)-6-[(2R,3S)-3-({[(4-Chloro-2-methylphenyl)sulfonyl]amino}methyl)bicyclo[2.2.2]oct-2-yl]-5-hexenoic acid

5-Hexenoic acid, 6-[(2R,3S)-3-[[[(4-chloro-2-methylphenyl)sulfonyl]amino]methyl]bicyclo[2.2.2]oct-2-yl]-, (5Z)-

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ONO-8711
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: ONO-8711
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Get all suppliers and price by the below link:

ONO-8711 suppliers

ONO-8711 price

ONO-8711

Use of ONO-8711

Names

ONO-8711 Biological Activity

Chemical & Physical Properties

Synonyms