ONO-8711
Modify Date: 2024-01-08 09:20:19
ONO-8711 structure
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Common Name | ONO-8711 | ||
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| CAS Number | 216158-34-8 | Molecular Weight | 439.996 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 605.2±65.0 °C at 760 mmHg | |
| Molecular Formula | C22H30ClNO4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 319.8±34.3 °C | |
Use of ONO-8711ONO-8711 is a potent and selective competitive antagonist of EP1 receptor (Ki = 0.6 and 1.7 nM for human and mouse EP1 respectively). ONO-8711 effectively reduces tumor incidence and multiplicity in mouse models of colon, breast, and oral cancer[1]. |
| Name | (Z)-6-[(2S,3R)-2-[[(4-chloro-2-methylphenyl)sulfonylamino]methyl]-3-bicyclo[2.2.2]octanyl]hex-5-enoic acid |
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| Synonym | More Synonyms |
| Description | ONO-8711 is a potent and selective competitive antagonist of EP1 receptor (Ki = 0.6 and 1.7 nM for human and mouse EP1 respectively). ONO-8711 effectively reduces tumor incidence and multiplicity in mouse models of colon, breast, and oral cancer[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 605.2±65.0 °C at 760 mmHg |
| Molecular Formula | C22H30ClNO4S |
| Molecular Weight | 439.996 |
| Flash Point | 319.8±34.3 °C |
| Exact Mass | 439.158417 |
| PSA | 91.85000 |
| LogP | 6.01 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.580 |
| (5Z)-6-[(2R,3S)-3-({[(4-Chloro-2-methylphenyl)sulfonyl]amino}methyl)bicyclo[2.2.2]oct-2-yl]-5-hexenoic acid |
| 5-Hexenoic acid, 6-[(2R,3S)-3-[[[(4-chloro-2-methylphenyl)sulfonyl]amino]methyl]bicyclo[2.2.2]oct-2-yl]-, (5Z)- |