Pipazethate

Modify Date: 2025-08-27 18:21:19

Pipazethate structure	Common Name	Pipazethate
	CAS Number	2167-85-3	Molecular Weight	399.50700
	Density	1.26g/cm3	Boiling Point	553.3ºC at 760mmHg
	Molecular Formula	C₂₁H₂₅N₃O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	288.4ºC

Use of Pipazethate

Pipazethate (SKF 70230A), a pyridobenzothiazine derivative, is a potent GABA antagonist. Pipazethate has antitussive activity. Pipazethate can be used in research in cough supressant[1].

Name	2-(2-piperidin-1-ylethoxy)ethyl pyrido[3,2-b][1,4]benzothiazine-10-carboxylate
Synonym	More Synonyms

Description	Pipazethate (SKF 70230A), a pyridobenzothiazine derivative, is a potent GABA antagonist. Pipazethate has antitussive activity. Pipazethate can be used in research in cough supressant[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Signaling Pathways >> Neuronal Signaling >> GABA Receptor

Density	1.26g/cm3
Boiling Point	553.3ºC at 760mmHg
Molecular Formula	C₂₁H₂₅N₃O₃S
Molecular Weight	399.50700
Flash Point	288.4ºC
Exact Mass	399.16200
PSA	80.20000
LogP	4.32630
Vapour Pressure	2.76E-12mmHg at 25°C
Index of Refraction	1.612
InChIKey	DTVJXCOMJLLMAK-UHFFFAOYSA-N
SMILES	O=C(OCCOCCN1CCCCC1)N1c2ccccc2Sc2cccnc21

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU8485000

CHEMICAL NAME :: 10H-Pyrido(3,2-b)(1,4)benzothiazine-10-carboxylic acid, 2-(2-(1-piperidinyl)ethoxy) ethyl ester

CAS REGISTRY NUMBER :: 2167-85-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C21-H25-N3-O3-S

MOLECULAR WEIGHT :: 399.55

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 94647 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 188,189,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 13140 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 188,189,1970

1H-Pyrido[3,2-b...

CAS#:261-96-1

Pipazethate

CAS#:2167-85-3

Literature: Schuler,W.A. et al. Justus Liebigs Annalen der Chemie, 1964 , vol. 673, p. 102 - 112

2-(2-(Piperidyl...

CAS#:3603-43-8

10H-pyrido[3,2-...

CAS#:94231-78-4

Pipazethate

CAS#:2167-85-3

Literature: Schuler,W.A. et al. Justus Liebigs Annalen der Chemie, 1964 , vol. 673, p. 102 - 112

Precursor 3
CAS#:261-96-1 1H-Pyrido[3,2-b... CAS#:3603-43-8 2-(2-(Piperidyl... CAS#:94231-78-4 10H-pyrido[3,2-...
DownStream 0

4-Aza-phenothiazin-10-carbonsaeure-piperidino-aethoxy-aethylester

Pipazetato [INN-Spanish]

Pipazetate

Pipazetatum [INN-Latin]

pipazethate

Theratuss

benzo[b]pyrido[2,3-e][1,4]thiazine-10-carboxylic acid 2-(2-piperidin-1-yl-ethoxy)-ethyl ester

Lenopect

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Pipazethate

Use of Pipazethate

Names

Pipazethate Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.