Z-Val-Asp-Val-Ala-Asp-AFC

Modify Date: 2026-08-14 09:49:08

Z-Val-Asp-Val-Ala-Asp-AFC Structure
Z-Val-Asp-Val-Ala-Asp-AFC structure
Common Name Z-Val-Asp-Val-Ala-Asp-AFC
CAS Number 219138-08-6 Molecular Weight 862.80
Density N/A Boiling Point N/A
Molecular Formula C39H45F3N6O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Z-Val-Asp-Val-Ala-Asp-AFC


Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name z-vdvad-afc
Synonym More Synonyms

 Z-Val-Asp-Val-Ala-Asp-AFC Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1].
Related Catalog
References

[1]. Pallepati P, et, al. Mild thermotolerance induced at 40°C protects HeLa cells against activation of death receptor-mediated apoptosis by hydrogen peroxide. Free Radic Biol Med. 2011 Mar 15;50(6):667-79.  

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Molecular Formula C39H45F3N6O13
Molecular Weight 862.80
Exact Mass 862.30000
PSA 288.64000
LogP 4.29330
Storage condition -15°C

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Z-Val-Asp-Ala-Asp-AFC
PASE-2 SUBSTRATE I,FLUOROGENIC
Z-VAL-ASP-VAL-ALA-ASP-AFC

 Z-Val-Asp-Val-Ala-Asp-AFC | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the CAS number of z-vdvad-afc?
A: CAS number of z-vdvad-afc is 219138-08-6.
Q: What are the storage conditions for z-vdvad-afc?
A: Storage conditions for z-vdvad-afc: -15°C.
Q: What English synonyms does z-vdvad-afc have?
A: English synonyms of z-vdvad-afc: Z-Val-Asp-Ala-Asp-AFC, PASE-2 SUBSTRATE I,FLUOROGENIC, Z-VAL-ASP-VAL-ALA-ASP-AFC.
Q: What is the molecular formula of z-vdvad-afc?
A: Molecular formula of z-vdvad-afc is C39H45F3N6O13.
Q: What is the English name of z-vdvad-afc?
A: The English name of z-vdvad-afc is z-vdvad-afc.
Q: What are the uses of z-vdvad-afc?
A: Main uses of z-vdvad-afc: Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1].
Q: What is the LogP of z-vdvad-afc?
A: LogP of z-vdvad-afc is 4.29330.
Q: What is the polar surface area (PSA) of z-vdvad-afc?
A: Polar surface area (PSA) of z-vdvad-afc is 288.64000.
Q: What is the molecular weight of z-vdvad-afc?
A: Molecular weight of z-vdvad-afc is 862.80.

 Z-Val-Asp-Val-Ala-Asp-AFCfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

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