Radequinil

Modify Date: 2024-01-10 17:05:03

Radequinil Structure
Radequinil structure
Common Name Radequinil
CAS Number 219846-31-8 Molecular Weight 334.33
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C18H14N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Radequinil


Radequinil (AC-3933) is a benzodiazepine receptor (BzR) partial inverse agonist. AC-3933 binds to GABA(-) and GABA(+) ligand with Kis of 5.15 and 6.11 nM, respectively[1].

 Names

Name Radequinil
Synonym More Synonyms

 Radequinil Biological Activity

Description Radequinil (AC-3933) is a benzodiazepine receptor (BzR) partial inverse agonist. AC-3933 binds to GABA(-) and GABA(+) ligand with Kis of 5.15 and 6.11 nM, respectively[1].
Related Catalog
Target

Ki: 5.15±0.39 nM (GABA(-) ligand), 6.11±0.26 nM (GABA(+) ligand)[1]

References

[1]. Hashimoto T, et al. Pharmacological properties of AC-3933, a novel benzodiazepine receptor partial inverse agonist. Neuroscience. 2014 Jan 3;256:352-9.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C18H14N4O3
Molecular Weight 334.33
Exact Mass 334.106598
LogP 2.54
Index of Refraction 1.620

 Synonyms

UNII-2G222T03EY
2G222T03EY
Radequinil
1,6-Naphthyridin-2(1H)-one, 5-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-
5-(3-Methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-1,6-naphthyridin-2(1H)-one
5-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-2-oxo-1,2-dihydro-1,6-naphthyridine
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