Selamectin
Selamectin structure
|
Common Name | Selamectin | ||
|---|---|---|---|---|
| CAS Number | 220119-17-5 | Molecular Weight | 769.960 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 917.0±65.0 °C at 760 mmHg | |
| Molecular Formula | C43H63NO11 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 508.4±34.3 °C | |
Use of SelamectinSelamectin is an anthelminthic which can be used on dogs and cats. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Selamectin |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Selamectin is an anthelminthic which can be used on dogs and cats. |
|---|---|
| Related Catalog | |
| In Vivo | Three monthly treatments with Selamectin/sarolaner provide high and consistent efficacy against I. ricinus for the entire duration of the study period. The percentage efficacy against I. ricinus is numerically higher in the Selemectin/sarolaner treating group than in the fluralaner-treating group on Days 56, 84 and 91[1]. All dogs are tested negative by both tests after receiving topical treatment with Selamectin monthly for 36 months[2]. |
| Animal Admin | The cats are weighed on Days-2, 29 and 58 to calculate the dosing. Cats in group 1 (control group) remain untreated. On Day 0, the cats in group 3 are treated with fluralaner at the minimum recommending label dose of 40.0 mg per kg body weight. On Days 0, 30 and 60, the cats in group 2 are treated with the new spot-on formulation at the minimum recommending label dose of 1.0 mg/kg sarolaner and 6.0 mg/kg Selamectin. The cats are observed at different time points after treatment for possible adverse reactions to treatment. On Day 0, administration site observations are performed on all cats 30 min (±5 min), 3 h (±15 min) and 24 h (±1 h) and again on Days 3 and 5 after treatment[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 917.0±65.0 °C at 760 mmHg |
| Molecular Formula | C43H63NO11 |
| Molecular Weight | 769.960 |
| Flash Point | 508.4±34.3 °C |
| Exact Mass | 769.440125 |
| PSA | 154.73000 |
| LogP | 6.83 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.618 |
| InChIKey | AFJYYKSVHJGXSN-BDOFTXKBSA-N |
| SMILES | COC1CC(OC2C(C)=CCC3CC(CC4(CCC(C)C(C5CCCCC5)O4)O3)OC(=O)C3C=C(C)C(=NO)C4OCC(=CC=CC2C)C34O)OC(C)C1O |
| Storage condition | 2-8°C |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| RIDADR | NONH for all modes of transport |
|---|
This table lists relevant public references with title, journal and publication metadata for this compound.
|
Determination of avermectins: a QuEChERS approach to the analysis of food samples.
Food Chem. 181 , 57-63, (2015) We present a simple method for extracting avermectines from meat, based on a QuEChERS approach followed by liquid chromatography (LC) coupled to triple quadrupole (QqQ) tandem mass spectrometry (MS/MS... |
|
|
The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer.
EMBO Mol. Med. 6(10) , 1263-78, (2014) Constitutive activation of canonical WNT-TCF signaling is implicated in multiple diseases, including intestine and lung cancers, but there are no WNT-TCF antagonists in clinical use. We have performed... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| (2aE,4E,5'S,6S,6'S,7S,8E,11R,13R,15S,17aR,20Z,20aR,20bS)-6'-cyclohexyl-20b-hydroxy-20-(hydroxyimino)-5',6,8,19-tetramethyl-17-oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranoside |
| (1'R,2R,4'S,5S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'Z,24'S)-6-Cyclohexyl-24'-hydroxy-21'-(hydroxyimino)-5,11',13',22'-tetramethyl-2'-oxo-3,4,5,6-tetrahydrospiro[pyran-2,6'-[3,7,19]trioxatetracyclo[ ;15.6.1.1.0]pentacosa[10,14,16,22]tetraen]-12'-yl 2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranoside |
| hypnocarpic acid |
| (1'R,2R,4'S,5S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'Z,24'S)-6-Cyclohexyl-24'-hydroxy-21'-(hydroxyimino)-5,11',13',22'-tetramethyl-2'-oxo-3,4,5,6-tetrahydrospiro[pyran-2,6'-[3,7,19]trioxatetracyclo[15.6.1.1.0]pentacosa[10,14,16,22]tetraen]-12'-yl-2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranoside |
| (1'R,2R,4'S,5S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'Z,24'S)-6-Cyclohexyl-24'-hydroxy-21'-(hydroxyimino)-5,11',13',22'-tetramethyl-2'-oxo-3,4,5,6-tetrahydrospiro[pyran-2,6'-[3,7,19]trioxatetracyclo[15.6.1.1.0]pentacosa[10,14,16,22]tetraen]-12'-yl 2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranoside |
| Stronghold |
| Selamectin |
| Revolution |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the LogP of Selamectin? |
| A: LogP of Selamectin is 6.83. |
| Q: What is the SMILES notation of Selamectin? |
| A: SMILES notation of Selamectin is COC1CC(OC2C(C)=CCC3CC(CC4(CCC(C)C(C5CCCCC5)O4)O3)OC(=O)C3C=C(C)C(=NO)C4OCC(=CC=CC2C)C34O)OC(C)C1O. |
| Q: What is the molecular weight of Selamectin? |
| A: Molecular weight of Selamectin is 769.960. |
| Q: What is the English name of Selamectin? |
| A: The English name of Selamectin is Selamectin. |
| Q: What is the InChIKey of Selamectin? |
| A: InChIKey of Selamectin is AFJYYKSVHJGXSN-BDOFTXKBSA-N. |
| Q: What are the uses of Selamectin? |
| A: Main uses of Selamectin: Selamectin is an anthelminthic which can be used on dogs and cats. |
| Q: What are the storage conditions for Selamectin? |
| A: Storage conditions for Selamectin: 2-8°C. |
| Q: What is the polar surface area (PSA) of Selamectin? |
| A: Polar surface area (PSA) of Selamectin is 154.73000. |
| Q: What is the boiling point of Selamectin? |
| A: Boiling point of Selamectin is 917.0±65.0 °C at 760 mmHg. |
| Q: What is the CAS number of Selamectin? |
| A: CAS number of Selamectin is 220119-17-5. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Henan Tianfu Chemical Co., Ltd. |