Selamectin structure 
             | 
        Common Name | Selamectin | ||
|---|---|---|---|---|
| CAS Number | 220119-17-5 | Molecular Weight | 769.960 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 917.0±65.0 °C at 760 mmHg | |
| Molecular Formula | C43H63NO11 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 508.4±34.3 °C | |
            Use of SelamectinSelamectin is an anthelminthic which can be used on dogs and cats.  | 
    
| Name | Selamectin | 
|---|---|
| Synonym | More Synonyms | 
| Description | Selamectin is an anthelminthic which can be used on dogs and cats. | 
|---|---|
| Related Catalog | |
| In Vivo | Three monthly treatments with Selamectin/sarolaner provide high and consistent efficacy against I. ricinus for the entire duration of the study period. The percentage efficacy against I. ricinus is numerically higher in the Selemectin/sarolaner treating group than in the fluralaner-treating group on Days 56, 84 and 91[1]. All dogs are tested negative by both tests after receiving topical treatment with Selamectin monthly for 36 months[2]. | 
| Animal Admin | The cats are weighed on Days-2, 29 and 58 to calculate the dosing. Cats in group 1 (control group) remain untreated. On Day 0, the cats in group 3 are treated with fluralaner at the minimum recommending label dose of 40.0 mg per kg body weight. On Days 0, 30 and 60, the cats in group 2 are treated with the new spot-on formulation at the minimum recommending label dose of 1.0 mg/kg sarolaner and 6.0 mg/kg Selamectin. The cats are observed at different time points after treatment for possible adverse reactions to treatment. On Day 0, administration site observations are performed on all cats 30 min (±5 min), 3 h (±15 min) and 24 h (±1 h) and again on Days 3 and 5 after treatment[1]. | 
| References | 
| Density | 1.4±0.1 g/cm3 | 
|---|---|
| Boiling Point | 917.0±65.0 °C at 760 mmHg | 
| Molecular Formula | C43H63NO11 | 
| Molecular Weight | 769.960 | 
| Flash Point | 508.4±34.3 °C | 
| Exact Mass | 769.440125 | 
| PSA | 154.73000 | 
| LogP | 6.83 | 
| Vapour Pressure | 0.0±0.6 mmHg at 25°C | 
| Index of Refraction | 1.618 | 
| Storage condition | 2-8°C | 
| RIDADR | NONH for all modes of transport | 
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                                    Determination of avermectins: a QuEChERS approach to the analysis of food samples.
                                    
                                    
                                     Food Chem. 181 , 57-63, (2015) We present a simple method for extracting avermectines from meat, based on a QuEChERS approach followed by liquid chromatography (LC) coupled to triple quadrupole (QqQ) tandem mass spectrometry (MS/MS...  | 
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                                    The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer.
                                    
                                    
                                     EMBO Mol. Med. 6(10) , 1263-78, (2014) Constitutive activation of canonical WNT-TCF signaling is implicated in multiple diseases, including intestine and lung cancers, but there are no WNT-TCF antagonists in clinical use. We have performed...  | 
                                
| (2aE,4E,5'S,6S,6'S,7S,8E,11R,13R,15S,17aR,20Z,20aR,20bS)-6'-cyclohexyl-20b-hydroxy-20-(hydroxyimino)-5',6,8,19-tetramethyl-17-oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranoside | 
| (1'R,2R,4'S,5S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'Z,24'S)-6-Cyclohexyl-24'-hydroxy-21'-(hydroxyimino)-5,11',13',22'-tetramethyl-2'-oxo-3,4,5,6-tetrahydrospiro[pyran-2,6'-[3,7,19]trioxatetracyclo[ ;15.6.1.1.0]pentacosa[10,14,16,22]tetraen]-12'-yl 2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranoside | 
| hypnocarpic acid | 
| (1'R,2R,4'S,5S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'Z,24'S)-6-Cyclohexyl-24'-hydroxy-21'-(hydroxyimino)-5,11',13',22'-tetramethyl-2'-oxo-3,4,5,6-tetrahydrospiro[pyran-2,6'-[3,7,19]trioxatetracyclo[15.6.1.1.0]pentacosa[10,14,16,22]tetraen]-12'-yl-2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranoside | 
| (1'R,2R,4'S,5S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'Z,24'S)-6-Cyclohexyl-24'-hydroxy-21'-(hydroxyimino)-5,11',13',22'-tetramethyl-2'-oxo-3,4,5,6-tetrahydrospiro[pyran-2,6'-[3,7,19]trioxatetracyclo[15.6.1.1.0]pentacosa[10,14,16,22]tetraen]-12'-yl 2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranoside | 
| Stronghold | 
| Selamectin | 
| Revolution |