Gunagratinib

Modify Date: 2024-01-06 21:39:07

Gunagratinib Structure
Gunagratinib structure
Common Name Gunagratinib
CAS Number 2211082-53-8 Molecular Weight 423.47
Density N/A Boiling Point N/A
Molecular Formula C22H25N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Gunagratinib


Gunagratinib (ICP-192) is a low toxicity and orally active pan-FGFR (fibroblast growth factor receptors) inhibitor that potently and selectively inhibits FGFR activities irreversibly by covalent binding. Gunagratinib can be used for the research of cancer[1].

 Names

Name Gunagratinib

 Gunagratinib Biological Activity

Description Gunagratinib (ICP-192) is a low toxicity and orally active pan-FGFR (fibroblast growth factor receptors) inhibitor that potently and selectively inhibits FGFR activities irreversibly by covalent binding. Gunagratinib can be used for the research of cancer[1].
Related Catalog
Target

FGFR

In Vitro Gunagratinib (ICP-192) is a low toxicity and orally active pan-FGFR (fibroblast growth factor receptors) inhibitor that potently and selectively inhibits FGFR activities irreversibly by covalent binding[1].
References

[1]. Guo Ye, et al. Phase I result of ICP-192 (gunagratinib), a highly selective irreversible FGFR inhibitor, in patients with advanced solid tumors harboring FGFR pathway alterations. Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021) 4092-4092.

 Chemical & Physical Properties

Molecular Formula C22H25N5O4
Molecular Weight 423.47
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