Podocarpusflavone A
Modify Date: 2024-01-02 17:27:56
Podocarpusflavone A structure
|
Common Name | Podocarpusflavone A | ||
|---|---|---|---|---|
| CAS Number | 22136-74-9 | Molecular Weight | 552.484 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 879.3±65.0 °C at 760 mmHg | |
| Molecular Formula | C31H20O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 295.2±27.8 °C | |
Use of Podocarpusflavone APodocarpusflavone A is a DNA topoisomerase I inhibitor, have moderated anti-proliferative activity induce cell apoptosis in MCF-7, is developing anti-tumor drugstarget: DNA topoisomerase IIn vitro: podocarpusflavone-A show significant inhibitions against DLD, KB, MCF-7, HEp-2 tumor cell lines (ED50 4.56-16.24 μg/mL) and induce cell apoptosis in MCF-7 via mainly sub-G1/S phase arrest. PF (40 ug/mL, 24 hr) significantly induced about 10 folds of cell deaths and growth arrest in S-phase than the control group. |
| Name | 8-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenyl]-5,7-d ihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one |
|---|---|
| Synonym | More Synonyms |
| Description | Podocarpusflavone A is a DNA topoisomerase I inhibitor, have moderated anti-proliferative activity induce cell apoptosis in MCF-7, is developing anti-tumor drugstarget: DNA topoisomerase IIn vitro: podocarpusflavone-A show significant inhibitions against DLD, KB, MCF-7, HEp-2 tumor cell lines (ED50 4.56-16.24 μg/mL) and induce cell apoptosis in MCF-7 via mainly sub-G1/S phase arrest. PF (40 ug/mL, 24 hr) significantly induced about 10 folds of cell deaths and growth arrest in S-phase than the control group. |
|---|---|
| Related Catalog | |
| Target |
Topoisomerase I:119.425 μM (IC50) |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 879.3±65.0 °C at 760 mmHg |
| Molecular Formula | C31H20O10 |
| Molecular Weight | 552.484 |
| Flash Point | 295.2±27.8 °C |
| Exact Mass | 552.105652 |
| PSA | 170.80000 |
| LogP | 4.15 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.750 |
| Storage condition | 2-8℃ |
| 8-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one |
| Podocarpusflavone A |
| 4H-1-Benzopyran-4-one, 8-(5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl)-5,7-dihydroxy-2-(4-methoxyphenyl)- |
| 9-Methylacridin |
| 4-Methylakridin |
| 4'''-methylamentoflavone |
| 4-Methylacridin |
| 1-Methylacridin |
| ACRIDINE,4-METHYL |
| 4H-1-Benzopyran-4-one, 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-methoxyphenyl)- |
| 4-methyl-acridine |
- Shanghai Nianxing Industrial Co., Ltd
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- Product Name: Podocarpusflavone A
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- China
- Product Name: podocarpusflavone A
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
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- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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