GSK3395879

Modify Date: 2024-01-19 12:06:30

GSK3395879 Structure
GSK3395879 structure
Common Name GSK3395879
CAS Number 2215852-91-6 Molecular Weight 485.41
Density N/A Boiling Point N/A
Molecular Formula C20H15F4N3O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GSK3395879


GSK3395879 is a selective and orally bioavailable transient receptor potential vanilloid-4 (TRPV4) antagonist with an IC50 of 1 nM for hTRPV4[1].

 Names

Name GSK3395879

 GSK3395879 Biological Activity

Description GSK3395879 is a selective and orally bioavailable transient receptor potential vanilloid-4 (TRPV4) antagonist with an IC50 of 1 nM for hTRPV4[1].
Related Catalog
Target

IC50: 1 nM (hTRPV4)[1]

References

[1]. Brnardic EJ, et al. Discovery of Pyrrolidine Sulfonamides as Selective and Orally Bioavailable Antagonists of Transient Receptor Potential Vanilloid-4 (TRPV4). J Med Chem. 2018 Nov 8;61(21):9738-9755.

 Chemical & Physical Properties

Molecular Formula C20H15F4N3O5S
Molecular Weight 485.41