T-Boc-n-amido-peg15-amine

Modify Date: 2024-01-08 20:47:39

T-Boc-n-amido-peg15-amine Structure
T-Boc-n-amido-peg15-amine structure
Common Name T-Boc-n-amido-peg15-amine
CAS Number 2222566-55-2 Molecular Weight 821.00
Density N/A Boiling Point N/A
Molecular Formula C37H76N2O17 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of T-Boc-n-amido-peg15-amine


Boc-NH-PEG15-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-NH-PEG15-NH2
Synonym More Synonyms

 T-Boc-n-amido-peg15-amine Biological Activity

Description Boc-NH-PEG15-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C37H76N2O17
Molecular Weight 821.00

 Synonyms

MFCD28385469
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