ADH-6

Modify Date: 2024-01-02 16:23:19

ADH-6 structure	Common Name	ADH-6
	CAS Number	2227429-65-2	Molecular Weight	640.64
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₃₆N₈O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ADH-6

ADH-6 is a tripyridylamide compound. ADH-6 abrogates self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD. ADH-6 targets and dissociates mutant p53 aggregates in human cancer cells, which restores p53's transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 has the potential for the research of cancer diseases[1].

Name	ADH-6

Description	ADH-6 is a tripyridylamide compound. ADH-6 abrogates self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD. ADH-6 targets and dissociates mutant p53 aggregates in human cancer cells, which restores p53's transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 has the potential for the research of cancer diseases[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Palanikumar L, et al. Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function. Nat Commun. 2021;12(1):3962.

Molecular Formula	C₂₉H₃₆N₈O₉
Molecular Weight	640.64

DC Chemicals Limited
China
Product Name: ADH-6
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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ADH-6

Use of ADH-6

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ADH-6 Biological Activity

Chemical & Physical Properties