2-methyl-3-(3-methylphenyl)quinazolin-4-one

Modify Date: 2025-09-19 20:56:07

2-methyl-3-(3-methylphenyl)quinazolin-4-one Structure
2-methyl-3-(3-methylphenyl)quinazolin-4-one structure
Common Name 2-methyl-3-(3-methylphenyl)quinazolin-4-one
CAS Number 22288-99-9 Molecular Weight 250.29500
Density 1.16g/cm3 Boiling Point 425.2ºC at 760 mmHg
Molecular Formula C16H14N2O Melting Point N/A
MSDS N/A Flash Point 210.9ºC

 Names

Name 2-methyl-3-(3-methylphenyl)quinazolin-4-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.16g/cm3
Boiling Point 425.2ºC at 760 mmHg
Molecular Formula C16H14N2O
Molecular Weight 250.29500
Flash Point 210.9ºC
Exact Mass 250.11100
PSA 34.89000
LogP 3.00250
Vapour Pressure 1.96E-07mmHg at 25°C
Index of Refraction 1.623
InChIKey ACZZXQREKJMALJ-UHFFFAOYSA-N
SMILES Cc1cccc(-n2c(C)nc3ccccc3c2=O)c1

 Synthetic Route

~71%

2-methyl-3-(3-methylphenyl)quinazolin-4-one Structure

2-methyl-3-(3-m...

CAS#:22288-99-9

Literature: Su; Wu; Xie; Li Organic Preparations and Procedures International, 2006 , vol. 38, # 1 p. 89 - 94

~70%

2-methyl-3-(3-methylphenyl)quinazolin-4-one Structure

2-methyl-3-(3-m...

CAS#:22288-99-9

Literature: Hydra Biosciences, Inc. Patent: US2007/179164 A1, 2007 ; Location in patent: Page/Page column 50; 51 ;

~41%

2-methyl-3-(3-methylphenyl)quinazolin-4-one Structure

2-methyl-3-(3-m...

CAS#:22288-99-9

Literature: Hilmy, Khalid Mohamed Hassan; Mogensen, Joergen; Pedersen, Erik B. Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, p. 467 - 468

 Bioassay

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Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
Name: AlphaScreen-based biochemical high throughput primary assay to identify activators of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: FBW7_ACT_ALPHA_1536_1X%ACT PRUN
Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN
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 Synonyms

2-methyl-3-m-tolyl-3H-quinazolin-4-one
2-Methyl-3-m-tolyl-3H-chinazolin-4-on
2-Methyl-3-o-tolyl-4-chinazolon
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