SOS1 activator 1
Modify Date: 2025-08-25 16:28:06
SOS1 activator 1 structure
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Common Name | SOS1 activator 1 | ||
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| CAS Number | 2245237-53-8 | Molecular Weight | 483.02 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H32ClFN6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SOS1 activator 1SOS1 activator 1 (Compound 64) is a potent activator of SOS1-mediated nucleotide exchange with a Kd of 44 nM. SOS1 is a guanine nucleotide exchange factor that catalyzes the exchange of GDP for GTP on RAS[1]. |
| Name | SOS1 activator 1 |
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| Description | SOS1 activator 1 (Compound 64) is a potent activator of SOS1-mediated nucleotide exchange with a Kd of 44 nM. SOS1 is a guanine nucleotide exchange factor that catalyzes the exchange of GDP for GTP on RAS[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C26H32ClFN6 |
|---|---|
| Molecular Weight | 483.02 |
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Name: Thermal Shift Assay. Domain: start/stop: N44-E168
Source: ChEMBL
Target: Bromodomain-containing protein 4
External Id: CHEMBL5060944
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Name: Thermal Shift Assay. Domain start/stop: M626-G740
Source: ChEMBL
Target: Peregrin
External Id: CHEMBL4650107
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Name: Thermal Shift Assay. Domain: start/stop: M1-L298
Source: ChEMBL
Target: Cyclin-dependent kinase 2
External Id: CHEMBL5062802
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Name: Activation of SOS1 in human HeLa cells expressing wild type KRAS assessed as increase...
Source: ChEMBL
Target: Son of sevenless homolog 1
External Id: CHEMBL4201763
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Name: Activation of SOS1 in human HeLa cells expressing wild type KRAS assessed as inductio...
Source: ChEMBL
Target: Son of sevenless homolog 1
External Id: CHEMBL4201762
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Name: Activation of SOS1 in human HeLa cells expressing wild type KRAS assessed as increase...
Source: ChEMBL
Target: Son of sevenless homolog 1
External Id: CHEMBL4201764
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|
Name: Thermal Shift Assay. Domain: start/stop: E122-S403
Source: ChEMBL
Target: Aurora kinase A
External Id: CHEMBL5067447
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|
Name: Thermal Shift Assay. Domain: start/stop: M1-K294
Source: ChEMBL
Target: Casein kinase I isoform delta
External Id: CHEMBL5063731
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|
Name: Thermal Shift Assay. Domain: start/stop: M26-R383
Source: ChEMBL
Target: Glycogen synthase kinase-3 beta
External Id: CHEMBL5065589
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Name: Thermal Shift Assay. Domain: start/stop: S229-K512
Source: ChEMBL
Target: Tyrosine-protein kinase ABL1
External Id: CHEMBL5060015
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