Fmoc-Ala-OH (2,3,3,3-D4)

Modify Date: 2024-04-05 23:00:13

Fmoc-Ala-OH (2,3,3,3-D4) Structure
Fmoc-Ala-OH (2,3,3,3-D4) structure
Common Name Fmoc-Ala-OH (2,3,3,3-D4)
CAS Number 225101-69-9 Molecular Weight 315.36
Density 1.3±0.1 g/cm3 Boiling Point 544.1±33.0 °C at 760 mmHg
Molecular Formula C18H13D4NO4 Melting Point 147-153ºC(lit.)
MSDS N/A Flash Point 282.9±25.4 °C

 Use of Fmoc-Ala-OH (2,3,3,3-D4)


Fmoc-Ala-OH-d4 is the deuterium labeled Fmoc-Ala-OH[1].

 Names

Name l-alanine-2,3,3,3-d4-n-fmoc
Synonym More Synonyms

 Fmoc-Ala-OH (2,3,3,3-D4) Biological Activity

Description Fmoc-Ala-OH-d4 is the deuterium labeled Fmoc-Ala-OH[1].
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 544.1±33.0 °C at 760 mmHg
Melting Point 147-153ºC(lit.)
Molecular Formula C18H13D4NO4
Molecular Weight 315.36
Flash Point 282.9±25.4 °C
Exact Mass 315.140869
PSA 75.63000
LogP 3.54
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.608

 Synonyms

L-Alanine-2,3,3,3-d, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-(2,3,3,3-H)alanine