Mal-amide-PEG2-oxyamine-Boc

Modify Date: 2024-01-09 18:35:29

Mal-amide-PEG2-oxyamine-Boc Structure
Mal-amide-PEG2-oxyamine-Boc structure
Common Name Mal-amide-PEG2-oxyamine-Boc
CAS Number 2253965-15-8 Molecular Weight 415.44
Density N/A Boiling Point N/A
Molecular Formula C18H29N3O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-amide-PEG2-oxyamine-Boc


Mal-amide-PEG2-oxyamineBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-amide-PEG2-oxyamine-Boc

 Mal-amide-PEG2-oxyamine-Boc Biological Activity

Description Mal-amide-PEG2-oxyamineBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C18H29N3O8
Molecular Weight 415.44