Rafoxanide

Modify Date: 2024-01-03 21:51:51

Rafoxanide Structure
Rafoxanide structure
Common Name Rafoxanide
CAS Number 22662-39-1 Molecular Weight 626.010
Density 2.0±0.1 g/cm3 Boiling Point 526.6±50.0 °C at 760 mmHg
Molecular Formula C19H11Cl2I2NO3 Melting Point 169ºC
MSDS Chinese USA Flash Point 272.3±30.1 °C

 Use of Rafoxanide


Rafoxanide is a salicylanilide used as an antiparasitic agent.

 Names

Name Rafoxanide
Synonym More Synonyms

 Rafoxanide Biological Activity

Description Rafoxanide is a salicylanilide used as an antiparasitic agent.
Related Catalog

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Boiling Point 526.6±50.0 °C at 760 mmHg
Melting Point 169ºC
Molecular Formula C19H11Cl2I2NO3
Molecular Weight 626.010
Flash Point 272.3±30.1 °C
Exact Mass 624.820496
PSA 58.56000
LogP 9.36
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.753
Storage condition 0-6°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VN7870000
CHEMICAL NAME :
Salicylanilide, 3'-chloro-4'-(p-chlorophenoxy)-3,5-diiodo-
CAS REGISTRY NUMBER :
22662-39-1
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C19-H11-Cl2-I2-N-O3
MOLECULAR WEIGHT :
626.01
WISWESSER LINE NOTATION :
QR BI DI FVMR CG DOR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - cattle
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
REMVAY Revue d'Elevage et de Medicine Veterinaire des Pays Tropicaux. (Editions Vigot, 23 rue de l'Ecole-de-Medecine, F-75006 Paris, France) V.1- 1947- Volume(issue)/page/year: 29,31,1976

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
RTECS VN7870000
HS Code 2924299090

 Preparation


 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles25

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The Hymenolepis diminuta-golden hamster (Mesocricetus auratus) model for the evaluation of gastrointestinal anticestode activity.

J. Parasitol. 90(4) , 898-9, (2004)

A novel laboratory anticestode assay was developed using Hymenolepis diminuta in the hamster. The commercial anticestode compounds, praziquantel, bunamidine, and niclosamide were active against patent...

An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide.

Toxicol. Lett. 208(1) , 30-5, (2012)

A number of environmental chemicals have been reported to exhibit thyroid hormone-like activity. Since thyroid hormones play a crucial role in development, it is important to identify chemicals in the...

Screening of closantel and rafoxanide in animal muscles by HPLC with fluorescence detection and confirmation using MS.

J. Sep. Sci. 33(2) , 206-11, (2010)

A sensitive and selective LC-FLD method was described for determination of closantel and rafoxanide in bovine and ovine muscles. Bovine and ovine muscles were extracted with ACN and acetone mixture (8...

 Synonyms

N-[3-Chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodobenzamide
EINECS 245-148-9
N-[3-Chlor-4-(4-chlorphenoxy)phenyl]-2-hydroxy-3,5-diiodbenzolcarboxamid
MFCD00682899
Rafoxanide
3'-Chloro-4'-(4-chlorophenoxy)-3,5-diiodosalicylanilide
3’-chloro-4’-(4-chlorophenoxy)-3,5-diiodosalicylanilide
Benzamide, N-(3-chloro-4-(4-chlorophenoxy)phenyl)-2-hydroxy-3,5-diiodo-
Benzamide, N-[3-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodo-
3'-Chlor-4'-<4-chlor-phenoxy>-3,5-dijod-salicyl-anilid
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