N-[(adamantan-1-yl)methyl]-2,5-dichlorobenzamide

Modify Date: 2025-08-28 23:45:37

N-[(adamantan-1-yl)methyl]-2,5-dichlorobenzamide Structure
N-[(adamantan-1-yl)methyl]-2,5-dichlorobenzamide structure
Common Name N-[(adamantan-1-yl)methyl]-2,5-dichlorobenzamide
CAS Number 227327-95-9 Molecular Weight 338.3
Density N/A Boiling Point N/A
Molecular Formula C18H21Cl2NO Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name N-[(adamantan-1-yl)methyl]-2,5-dichlorobenzamide

 Chemical & Physical Properties

Molecular Formula C18H21Cl2NO
Molecular Weight 338.3
InChIKey MQAXGMKOSXBMHT-UHFFFAOYSA-N
SMILES O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(Cl)ccc1Cl

 Bioassay

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Name: Intrinsic clearance in rat hepatocytes was determined
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL875276
Name: Volume of distribution at steady state in rat
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL1028696
Name: Half life in rat
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL1028697
Name: Metabolic stability in rat hepatocytes assessed as intrinsic clearance assessed per m...
Source: ChEMBL
Target: Hepatocyte
External Id: CHEMBL1028694
Name: Plasma clearance in rat
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL1028695
Name: Antagonistic activity against the P2X7 ion channel
Source: ChEMBL
Target: P2X purinoceptor 7
External Id: CHEMBL882189
Name: Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of Bz...
Source: ChEMBL
Target: P2X purinoceptor 7
External Id: CHEMBL1028693
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