HIP-B

Modify Date: 2023-01-17 18:21:43

HIP-B Structure
HIP-B structure
Common Name HIP-B
CAS Number 227619-65-0 Molecular Weight 172.14
Density N/A Boiling Point N/A
Molecular Formula C6H8N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HIP-B


(±)-HIP-B is a non-competitive excitatory amino acid transporter (EAAT) blocker that effectively blocks Glu uptake (IC50=17-18 μM). (±)-HIP-B is also a lead compound against ischemia-induced neuronal degeneration. (±)-HIP-B can be used in the study of neurological diseases[1].

 Names

Name (3aS,6S,6aS)-3-oxo-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d][1,2]oxazole-6-carboxylic acid
Synonym More Synonyms

 HIP-B Biological Activity

Description (±)-HIP-B is a non-competitive excitatory amino acid transporter (EAAT) blocker that effectively blocks Glu uptake (IC50=17-18 μM). (±)-HIP-B is also a lead compound against ischemia-induced neuronal degeneration. (±)-HIP-B can be used in the study of neurological diseases[1].
Related Catalog
References

[1]. Andrea Pinto, et al. Synthesis of enantiomerically pure HIP-A and HIP-B and investigation of their activity as inhibitors of excitatory amino acid transporters.

 Chemical & Physical Properties

Molecular Formula C6H8N2O4
Molecular Weight 172.14
Exact Mass 172.04800
PSA 91.15000

 Synonyms

hip-b