pH-Low Insertion Peptide

Modify Date: 2025-08-25 13:05:00

pH-Low Insertion Peptide Structure
pH-Low Insertion Peptide structure
Common Name pH-Low Insertion Peptide
CAS Number 2293160-09-3 Molecular Weight 4052.03
Density N/A Boiling Point N/A
Molecular Formula C189H28N4O55S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of pH-Low Insertion Peptide


pH-Low Insertion Peptide (pHLIP) used as a specific ligand to target the tumor acidic microenvironment for tumors at early and metastatic stages[1].

 Names

Name pH-Low Insertion Peptide

 pH-Low Insertion Peptide Biological Activity

Description pH-Low Insertion Peptide (pHLIP) used as a specific ligand to target the tumor acidic microenvironment for tumors at early and metastatic stages[1].
Related Catalog
References

[1]. Yushuang Wei, et al. pH-responsive pHLIP (pH low insertion peptide) nanoclusters of superparamagnetic iron oxide nanoparticles as a tumor-selective MRI contrast agent. Acta Biomater. 2017 Jun;55:194-203.  

 Chemical & Physical Properties

Molecular Formula C189H28N4O55S
Molecular Weight 4052.03
InChIKey GHOAMUSBZVQHHQ-XRCOSKEGSA-N
SMILES CCC(C)C(NC(=O)C1CCCN1C(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(=O)O)NC(=O)C(CS)NC(=O)C(C)N)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)NC(C(=O)NC(C(=O)N1CCCC1C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(C(=O)O)C(C)O)C(C)C)C(C)O)C(C)O
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