PROTAC ER Degrader-4

Modify Date: 2024-01-10 18:48:26

PROTAC ER Degrader-4 structure	Common Name	PROTAC ER Degrader-4
	CAS Number	2361114-15-8	Molecular Weight	1005.19
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₃H₆₇F₃N₆O₈S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PROTAC ER Degrader-4

PROTAC ER Degrader-4 is a PROATC estrogen receptor (ER) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC50 of 0.3 nM[1].

Name	PROTAC ER Degrader-4

Description	PROTAC ER Degrader-4 is a PROATC estrogen receptor (ER) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC50 of 0.3 nM[1].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC
Target	VHL ER
In Vitro	PROTAC ER Degrader-4 shows equal to 100% ER degradation at 0.3 μM in the MCF-7 ER degradation cellular assay[1].
References	[1]. Bin Yang, et al. Compounds and their use in treating cancer. WO2019123367A1.

Molecular Formula	C₅₃H₆₇F₃N₆O₈S
Molecular Weight	1005.19
Storage condition	2-8°C

DC Chemicals Limited
China
Product Name: PROTAC ER Degrader-4
Price:
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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