Kallikrein 5-IN-2

Modify Date: 2024-01-23 09:08:11

Kallikrein 5-IN-2 Structure
Kallikrein 5-IN-2 structure
Common Name Kallikrein 5-IN-2
CAS Number 2361160-57-6 Molecular Weight 398.46
Density N/A Boiling Point N/A
Molecular Formula C23H22N6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Kallikrein 5-IN-2


Kallikrein 5-IN-2 (compound 21) is a selective Kallikrein KLK5 inhibitor (pIC50=7.1). KLK5 inhibition may normalise epidermal shedding and reduce the associated inflammation and itching[1].

 Names

Name Kallikrein 5-IN-2

 Kallikrein 5-IN-2 Biological Activity

Description Kallikrein 5-IN-2 (compound 21) is a selective Kallikrein KLK5 inhibitor (pIC50=7.1). KLK5 inhibition may normalise epidermal shedding and reduce the associated inflammation and itching[1].
Related Catalog
Target

Kallikrein 5[1]

References

[1]. Walker AL, et al. Structure guided drug design to develop kallikrein 5 inhibitors to treat Netherton syndrome. Bioorg Med Chem Lett. 2019 Jun 15;29(12):1454-1458.  

 Chemical & Physical Properties

Molecular Formula C23H22N6O
Molecular Weight 398.46