Neogrifolin

Modify Date: 2024-01-18 10:26:12

Neogrifolin Structure
Neogrifolin structure
Common Name Neogrifolin
CAS Number 23665-96-5 Molecular Weight 328.49
Density N/A Boiling Point N/A
Molecular Formula C22H32O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Neogrifolin


Neogrifolin is an inhibitor of KRAS. Neogrifolin suppress KRAS expression in human colon cancer cells. Neogrifolin has anti-cell viability activity against HeLa, SW480 and HT29 cells wih IC50s of 24.3, 34.6, and 30.1 μM, respectively[1].

 Names

Name Neogrifolin
Synonym More Synonyms

 Neogrifolin Biological Activity

Description Neogrifolin is an inhibitor of KRAS. Neogrifolin suppress KRAS expression in human colon cancer cells. Neogrifolin has anti-cell viability activity against HeLa, SW480 and HT29 cells wih IC50s of 24.3, 34.6, and 30.1 μM, respectively[1].
Related Catalog
References

[1]. Yaqoob A, et al. Grifolin, neogrifolin and confluentin from the terricolous polypore Albatrellus flettii suppress KRAS expression in human colon cancer cells. PLoS One. 2020 May 5;15(5):e0231948.  

 Chemical & Physical Properties

Molecular Formula C22H32O2
Molecular Weight 328.49
Exact Mass 328.24000
PSA 40.46000
LogP 6.36790

 Synonyms

neogrifolin
5-Methyl-4-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-trienyl)-benzene-1,3-diol
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