Nardosinone
Modify Date: 2025-08-22 22:32:23
Nardosinone structure
|
Common Name | Nardosinone | ||
|---|---|---|---|---|
| CAS Number | 23720-80-1 | Molecular Weight | 250.333 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 330.2±32.0 °C at 760 mmHg | |
| Molecular Formula | C15H22O3 | Melting Point | 108-110℃ | |
| MSDS | N/A | Flash Point | 142.0±25.2 °C | |
Use of NardosinoneNardosinone, isolated from Nardostachys chinensis, is the first enhancer of the neuritogenic action of dbcAMP and staurosporine. Nardosinone may become a useful pharmacological tool for studying the mechanism of action of not only nerve growth factor (NGF) but also both the neuritogenic substances[1]. |
| Name | nardosinone |
|---|---|
| Synonym | More Synonyms |
| Description | Nardosinone, isolated from Nardostachys chinensis, is the first enhancer of the neuritogenic action of dbcAMP and staurosporine. Nardosinone may become a useful pharmacological tool for studying the mechanism of action of not only nerve growth factor (NGF) but also both the neuritogenic substances[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Nardosinone (0.1-100 microM) enhanced dibutyryl cyclic AMP (dbcAMP, 0.3 mM)- and staurosporine (10 nM)-induced neurite outgrowth from PC12D cells in a concentration-dependent manner. Nardosinone enhances a downstream step of MAP kinase in the MAP kinase-dependent signaling pathway[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 330.2±32.0 °C at 760 mmHg |
| Melting Point | 108-110℃ |
| Molecular Formula | C15H22O3 |
| Molecular Weight | 250.333 |
| Flash Point | 142.0±25.2 °C |
| Exact Mass | 250.156891 |
| PSA | 35.53000 |
| LogP | 3.04 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.522 |
| Storage condition | 2-8C |
| HS Code | 29145090 |
|---|
|
~50%
Nardosinone CAS#:23720-80-1 |
| Literature: Archiv der Pharmazie, , vol. 323, # 3 p. 171 - 175 |
|
~4%
Nardosinone CAS#:23720-80-1
Detail
|
| Literature: Archiv der Pharmazie, , vol. 323, # 3 p. 171 - 175 |
|
~50%
Nardosinone CAS#:23720-80-1 |
| Literature: Ruecker, Gerhard; Olbrich, Armin Tetrahedron Letters, 1988 , vol. 29, # 37 p. 4703 - 4704 |
|
~%
Nardosinone CAS#:23720-80-1
Detail
|
| Literature: Archiv der Pharmazie, , vol. 323, # 3 p. 171 - 175 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| Nardosinone |
| 5H-Naphtho[2,1-c][1,2]dioxol-5-one, 1,3a,4,7,8,9,9a,9b-octahydro-1,1,9,9a-tetramethyl-, (3aR,9R,9aR,9bS)- |
| 5H-Naphtho[2,1-c][1,2]dioxol-5-one,1,3a,4,7,8,9,9a,9b-octahydro-1,1,9,9a-tetramethyl-, (3aR,9R,9aR,9bS)- |
| (3aR,9R,9aR,9bS)-1,1,9,9a-Tetramethyl-1,3a,4,7,8,9,9a,9b-octahydro-5H-naphtho[2,1-c][1,2]dioxol-5-one |
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