MR-L2

Modify Date: 2024-04-08 21:17:41

MR-L2 Structure
MR-L2 structure
Common Name MR-L2
CAS Number 2374703-19-0 Molecular Weight 441.71
Density N/A Boiling Point N/A
Molecular Formula C19H16Cl3FN4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MR-L2


MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4), activates representative PDE4 long-isoform variants (PDE4A4, PDE4B1, PDE4C3, PDE4D5). MR-L2 suppresses PGE2-induced MDCK cell cyst formation with an EC50 of 1.2 μM.

 Names

Name MR-L2

 MR-L2 Biological Activity

Description MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4), activates representative PDE4 long-isoform variants (PDE4A4, PDE4B1, PDE4C3, PDE4D5). MR-L2 suppresses PGE2-induced MDCK cell cyst formation with an EC50 of 1.2 μM.

 Chemical & Physical Properties

Molecular Formula C19H16Cl3FN4O
Molecular Weight 441.71
Storage condition -20°C
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