DBCO-NH-(CH2)4COOH

Modify Date: 2024-01-31 00:15:29

DBCO-NH-(CH2)4COOH Structure
DBCO-NH-(CH2)4COOH structure
Common Name DBCO-NH-(CH2)4COOH
CAS Number 2375193-74-9 Molecular Weight 404.46
Density N/A Boiling Point N/A
Molecular Formula C24H24N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-NH-(CH2)4COOH


DBCO-NH-(CH2)4COOH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DBCO-NH-(CH2)4COOH

 DBCO-NH-(CH2)4COOH Biological Activity

Description DBCO-NH-(CH2)4COOH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C24H24N2O4
Molecular Weight 404.46