TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride

Modify Date: 2024-02-22 18:49:45

TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride Structure
TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride structure
Common Name TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride
CAS Number 2388520-36-1 Molecular Weight 873.47
Density N/A Boiling Point N/A
Molecular Formula C41H69ClN6O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride


TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate for ADC with potent antitumor activity by using TLR7/8 agonist 4 (HY-139018; a TLR7/8 agonist), linked via the cleavable ADC linker hydroxy-PEG10-acid (HY-133307)[1].

 Names

Name TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride

  Biological Activity

Description TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate for ADC with potent antitumor activity by using TLR7/8 agonist 4 (HY-139018; a TLR7/8 agonist), linked via the cleavable ADC linker hydroxy-PEG10-acid (HY-133307)[1].
Related Catalog
Target

Traditional Cytotoxic Agents

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Shelley Erin ACKERMAN, et al. Immunoconjugates targeting her2. WO2020190725A1.

 Chemical & Physical Properties

Molecular Formula C41H69ClN6O12
Molecular Weight 873.47