5-Carboxy-2-thiouracil

Modify Date: 2025-08-25 16:39:53

5-Carboxy-2-thiouracil Structure
5-Carboxy-2-thiouracil structure
Common Name 5-Carboxy-2-thiouracil
CAS Number 23945-50-8 Molecular Weight 172.16200
Density 1.74g/cm3 Boiling Point 461.2ºC at 760mmHg
Molecular Formula C5H4N2O3S Melting Point N/A
MSDS Chinese USA Flash Point 232.7ºC

 Names

Name 2-thiouracil-5-carboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.74g/cm3
Boiling Point 461.2ºC at 760mmHg
Molecular Formula C5H4N2O3S
Molecular Weight 172.16200
Flash Point 232.7ºC
Exact Mass 171.99400
PSA 122.11000
LogP 0.16910
Vapour Pressure 2.65E-09mmHg at 25°C
Index of Refraction 1.719
InChIKey XKHWTDCFQVKNHW-UHFFFAOYSA-N
SMILES O=C(O)c1c[nH]c(=S)[nH]c1=O

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933599090

 Synthetic Route

~%

5-Carboxy-2-thiouracil Structure

5-Carboxy-2-thi...

CAS#:23945-50-8

Literature: TOKUYAMA CORPORATION Patent: EP802194 A3, 1997 ;

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles2

More Articles
Synthesis, characterization and antitumour activity of metal complexes of 5-carboxy-2-thiouracil.

Met. Based Drugs 5 , 35-39, (1998)

Metal complexes of 5-carboxy-2-thiouracil with Mn(ll), Co(ll), Ni(ll), Cu(ll), Zn(ll) and Cd(ll) ions were synthesized, characterized, and subjected to a screening system for evaluation of antitumour ...

[Synthesis and antibacterial and antitumoral activity of some methylhydrazonium salts of pyrimidine bases and their analogues (author's transl)].

Pharmazie 37 , 355-356, (1982)

On reacting pyrimidine metabolites containing a carboxyl or sulfhydryl group with methylhydrazine or N-benzyl-N'-methylhydrazine, various methylhydrazonium salts of these metabolites were synthetized,...

 5-Carboxy-2-thiouracilBioassay

View more

Name: Antagonist cytotoxicity against human U-87MG cells assessed as reduction in cell viab...
Source: ChEMBL
Target: U-87 MG
External Id: CHEMBL5032438
Name: Synergistic cytotoxicity against human U-87MG cells assessed as combinantion index at...
Source: ChEMBL
Target: U-87 MG
External Id: CHEMBL5032442
Name: Induction of cell cycle arrest in human U-87MG cells assessed as accumulation of cell...
Source: ChEMBL
Target: U-87 MG
External Id: CHEMBL5032439
Name: Induction of DNA damage in human U-87MG cells assessed as increase in gamma H2AX phos...
Source: ChEMBL
Target: U-87 MG
External Id: CHEMBL5032434
Name: Antiproliferative activity against human U-87 MG cells incubated for 72 to 120 hrs by...
Source: ChEMBL
Target: U-87 MG
External Id: CHEMBL5032422
Name: Antiproliferative activity against human KARPAS-299 cells at 100 uM incubated for 48 ...
Source: ChEMBL
Target: KARPAS-299
External Id: CHEMBL5032421
Name: Antiproliferative activity against human HL-60 cells at 100 uM incubated for 48 hrs b...
Source: ChEMBL
Target: HL-60
External Id: CHEMBL5032419
Name: Antiproliferative activity against human HT-29 cells at 10 to 100 uM incubated for 72...
Source: ChEMBL
Target: HT-29
External Id: CHEMBL5032425
Name: Antiproliferative activity against human MKN-45 cells at 10 to 100 uM incubated for 7...
Source: ChEMBL
Target: MKN-45
External Id: CHEMBL5032423
Name: Antiproliferative activity against human MV4-11 cells at 100 uM incubated for 48 hrs ...
Source: ChEMBL
Target: MV4-11
External Id: CHEMBL5032414
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 Synonyms

4-Oxo-2-thioxo-1,2,3,4-tetrahydro-pyrimidin-5-carbonsaeure
5-Carboxy-2-thiouracil,2-Thiouracil-5-carboxylic acid,5-Carboxy-4-hydroxy-2-thiopyrimidine
1,2,3,4-tetrahydro-4-oxo-2-thioxo-5-pyrimidinecarboxylicaci
2-thioisoorotic acid
2-Thiouracil-5-carboxylic acid,5-Carboxy-4-hydroxy-2-thiopyrimidine
5-Carboxy-2-thiouracil
1,2,3,4-Tetrahydro-4-oxo-2-thioxo-5-pyrimidinecarboxylic acid
5-Carboxy-7-thiouracil
5-carboxy-2-thio-uracil
1,2,3,4-tetrahydro-4-oxo-2-thioxopyrimidine-5-carboxylic acid
4-oxo-2-thioxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid
5-carboxy-2-thiouracil free acid
5-CARBOXY-4-HYDROXY-2-THIOPYRIMIDINE
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