t-Boc-Aminooxy-PEG4-NHS ester

Modify Date: 2024-01-12 08:06:40

t-Boc-Aminooxy-PEG4-NHS ester structure	Common Name	t-Boc-Aminooxy-PEG4-NHS ester
	CAS Number	2401831-99-8	Molecular Weight	478.49
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₃₄N₂O₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of t-Boc-Aminooxy-PEG4-NHS ester

t-Boc-Aminooxy-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	t-Boc-Aminooxy-PEG4-NHS ester

Description	t-Boc-Aminooxy-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₀H₃₄N₂O₁₁
Molecular Weight	478.49