hCAII-IN-2

Modify Date: 2024-01-09 21:36:50

hCAII-IN-2 structure	Common Name	hCAII-IN-2
	CAS Number	2408599-78-8	Molecular Weight	519.96
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₁₈ClN₅O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of hCAII-IN-2

hCAII-IN-2 (Compound 11f) is a cytosolic human carbonic anhydrase (hCA) inhibitor with Ki values of 261.4, 3.8, 19.6 and 45.2 nM against hCA I, hCA II, hCA IX and hCA XII, respectively[1].

Name	hCAII-IN-2

Description	hCAII-IN-2 (Compound 11f) is a cytosolic human carbonic anhydrase (hCA) inhibitor with Ki values of 261.4, 3.8, 19.6 and 45.2 nM against hCA I, hCA II, hCA IX and hCA XII, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	Ki: 3.8 nM (hCA II), 19.6 nM (hCA IX), 45.2 nM (hCA XII), 261.4 nM (hCA I)[1]
References	[1]. Khalil OM, et al. Pyrrolo and pyrrolopyrimidine sulfonamides act as cytotoxic agents in hypoxia via inhibition of transmembrane carbonic anhydrases. Eur J Med Chem. 2020 Feb 15;188:112021.

Molecular Formula	C₂₅H₁₈ClN₅O₄S
Molecular Weight	519.96