EGFR-IN-64

Modify Date: 2024-01-09 19:29:17

EGFR-IN-64 structure	Common Name	EGFR-IN-64
	CAS Number	2416924-93-9	Molecular Weight	351.40
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₁N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of EGFR-IN-64

EGFR-IN-64 (Compound 3c) is a potent EGFR inhibitor with an IC50 of 0.33 μM. EGFR-IN-64 shows anticancer activity[1].

Name	EGFR-IN-64

Description	EGFR-IN-64 (Compound 3c) is a potent EGFR inhibitor with an IC50 of 0.33 μM. EGFR-IN-64 shows anticancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFR:0.33 μM (IC50)
In Vitro	EGFR-IN-64 (Compound 3c) shows cytotoxicity with IC50 values of 4.46 ± 0.11 μM and 16.23 ± 0.65 μM against MCF-7 and WI-38, respectively[1].
References	[1]. George RF, et al. Some 1,3,5-trisubstituted pyrazoline derivatives targeting breast cancer: Design, synthesis, cytotoxic activity, EGFR inhibition and molecular docking. Bioorg Chem. 2020 Jun;99:103780.

Molecular Formula	C₂₀H₂₁N₃O₃
Molecular Weight	351.40