(S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA

Modify Date: 2025-08-28 13:24:07

(S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA Structure
(S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA structure
Common Name (S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA
CAS Number 2417370-48-8 Molecular Weight 944.07
Density N/A Boiling Point N/A
Molecular Formula C38H56F3N5O13S3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA


(S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based ligand and 3-unit PEG linker used in PROTAC technology[1].

 Names

Name (S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA

  Biological Activity

Description (S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based ligand and 3-unit PEG linker used in PROTAC technology[1].
Related Catalog
References

[1]. Chan KH, et al. Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds. J Med Chem. 2018 Jan 25;61(2):504-513.  

 Chemical & Physical Properties

Molecular Formula C38H56F3N5O13S3
Molecular Weight 944.07
InChIKey CLEZKFFRUUBANA-WARMXROESA-N
SMILES Cc1ncsc1-c1ccc(CNC(=O)C2CC(OC(=O)OC(C)C(C)SS(C)(=O)=O)CN2C(=O)C(NC(=O)COCCOCCOCCN)C(C)(C)C)cc1.O=C(O)C(F)(F)F
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