PROTAC BRD4 Degrader-10

Modify Date: 2024-05-03 13:27:29

PROTAC BRD4 Degrader-10 Structure
PROTAC BRD4 Degrader-10 structure
Common Name PROTAC BRD4 Degrader-10
CAS Number 2417370-49-9 Molecular Weight 1312.50
Density N/A Boiling Point N/A
Molecular Formula C59H71F2N9O15S4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PROTAC BRD4 Degrader-10


PROTAC BRD4 Degrader-10 (compound 8b) is a potent BRD4 degrader. PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 1.3 nM and 18 nM, respectively.

 Names

Name PROTAC BRD4 Degrader-10

 PROTAC BRD4 Degrader-10 Biological Activity

Description PROTAC BRD4 Degrader-10 (compound 8b) is a potent BRD4 degrader. PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 1.3 nM and 18 nM, respectively.

 Chemical & Physical Properties

Molecular Formula C59H71F2N9O15S4
Molecular Weight 1312.50
Storage condition 2-8°C
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