adriamycinone

Modify Date: 2025-08-25 17:18:14

adriamycinone Structure
adriamycinone structure
 Common Name adriamycinone
CAS Number 24385-10-2 Molecular Weight 414.36200
Density 1.671g/cm3 Boiling Point 726.6ºC at 760 mmHg
Molecular Formula C21H18O9 Melting Point 223-225ºC
MSDS N/A Flash Point 260.4ºC

 Use of adriamycinone


Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin[1]. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively.

 Names

Name adriamycinone
Synonym More Synonyms

 adriamycinone Biological Activity

Description Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin[1]. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively.
Related Catalog
References

[1]. M Joerger, et al. Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma. Cancer Chemother Pharmacol. 2005 May;55(5):488-96.

 Chemical & Physical Properties

Density 1.671g/cm3
Boiling Point 726.6ºC at 760 mmHg
Melting Point 223-225ºC
Molecular Formula C21H18O9
Molecular Weight 414.36200
Flash Point 260.4ºC
Exact Mass 414.09500
PSA 161.59000
LogP 0.15390
Vapour Pressure 3.7E-22mmHg at 25°C
Index of Refraction 1.737
Storage condition Amber Vial, -20°C Freezer

 Synonyms

14-hydroxydaunomycinone
doxorubicin hydroxyaglycone
8-glycoloyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-Naphthacenedione
Epirubicin aglycone
Doxorubicinone
Epirubicin aglycon
doxorubicin aglycone
Adriamycin-aglycon
adriamycinaglycone
MFCD00871832
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