AC-42

Modify Date: 2025-08-25 17:57:02

AC-42 structure	Common Name	AC-42
	CAS Number	244291-63-2	Molecular Weight	301.47
	Density	0.958±0.06 g/cm3(Predicted)	Boiling Point	427.5±28.0 °C(Predicted)
	Molecular Formula	C₂₀H₃₁NO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AC-42

AC-42 is a poent M1 muscarinic selective allosteric agonist with EC50s of 805 nM and 220 nM for human wild-type and Y381A mutated M1 receptors, respectively[1].

Name	AC-42
Synonym	More Synonyms

Description	AC-42 is a poent M1 muscarinic selective allosteric agonist with EC50s of 805 nM and 220 nM for human wild-type and Y381A mutated M1 receptors, respectively[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
References	[1]. Marlene A Jacobson, et al. The M1 muscarinic receptor allosteric agonists AC-42 and 1-[1'-(2-methylbenzyl)-1,4'-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one bind to a unique site distinct from the acetylcholine orthosteric site. Mol Pharmacol. 2010 Oct;78(4):648-57.

Density	0.958±0.06 g/cm3(Predicted)
Boiling Point	427.5±28.0 °C(Predicted)
Molecular Formula	C₂₀H₃₁NO
Molecular Weight	301.47

AC 42

AC42

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