NAEPA

Modify Date: 2025-08-25 16:35:54

NAEPA Structure
NAEPA structure
Common Name NAEPA
CAS Number 24435-25-4 Molecular Weight 405.50900
Density N/A Boiling Point N/A
Molecular Formula C20H40NO5P Melting Point 75.8-84.0ºC
MSDS USA Flash Point N/A

 Use of NAEPA


NAEPA, a phosphate-mimetic derivative, is a lysophosphatidic acid (LPA) receptor agonist[1].

 Names

Name (Z)-N-[2-(Phosphonooxy)ethyl]-9-octadecenamide
Synonym More Synonyms

 NAEPA Biological Activity

Description NAEPA, a phosphate-mimetic derivative, is a lysophosphatidic acid (LPA) receptor agonist[1].
Related Catalog
References

[1]. Santos WL, et al. Synthesis and biological evaluation of phosphonic and thiophosphoric acid derivatives of lysophosphatidic acid. Bioorg Med Chem Lett. 2004;14(13):3473-3476.

 Chemical & Physical Properties

Melting Point 75.8-84.0ºC
Molecular Formula C20H40NO5P
Molecular Weight 405.50900
Exact Mass 405.26400
PSA 109.16000
LogP 6.08970
InChIKey BCSUWOZFWWBYSX-KTKRTIGZSA-N
SMILES CCCCCCCCC=CCCCCCCCC(=O)NCCOP(=O)(O)O

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles1

More Articles
Lysophosphatidic acid stimulates prostaglandin E2 production in cultured stromal endometrial cells through LPA1 receptor.

Exp. Biol. Med. 234 , 986-93, (2009)

Lysophosphatidic acid (LPA) has been shown to be a potent modulator of prostaglandin (PG) secretion during the luteal phase of the estrous cycle in the bovine endometrium in vivo. The aims of the pres...

 NAEPABioassay

View more

Name: Inhibition of Carbonic anhydrase 9 (unknown origin) using p-nitrophenyl acetate as su...
Source: ChEMBL
Target: Carbonic anhydrase 9
External Id: CHEMBL5332832
Name: Agonistic activity against lysophosphatidic acid receptor 1 using [35S]GTP-gamma-S as...
Source: ChEMBL
Target: Lysophosphatidic acid receptor 1
External Id: CHEMBL707058
Name: Inhibition of human NPP3 expressed in COS-7 cells using pNP-TMP as substrate preincub...
Source: ChEMBL
Target: Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
External Id: CHEMBL5332749
Name: Agonist activity at human LPA1 receptor transfected in HEK293T cells after 30 mins by...
Source: ChEMBL
Target: Lysophosphatidic acid receptor 1
External Id: CHEMBL3624257
Name: Maximal efficacy to that of maximal efficacy of LPA against lysophosphatidic acid rec...
Source: ChEMBL
Target: Lysophosphatidic acid receptor 1
External Id: CHEMBL707059
Name: Inhibition of human NPP1 expressed in COS-7 cells using pNP-TMP as substrate preincub...
Source: ChEMBL
Target: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
External Id: CHEMBL5332748
Name: Maximal efficacy to that of maximal efficacy of LPA against lysophosphatidic acid rec...
Source: ChEMBL
Target: Lysophosphatidic acid receptor 2
External Id: CHEMBL707062
Name: Agonistic activity against lysophosphatidic acid receptor 2 using [35S]GTP-gamma-S as...
Source: ChEMBL
Target: Lysophosphatidic acid receptor 2
External Id: CHEMBL707061
Name: Agonistic activity against lysophosphatidic acid receptor 3 using [35S]GTP-gamma-S as...
Source: ChEMBL
Target: Lysophosphatidic acid receptor 3
External Id: CHEMBL884413
Name: Maximal efficacy to that of maximal efficacy of LPA against lysophosphatidic acid rec...
Source: ChEMBL
Target: Lysophosphatidic acid receptor 3
External Id: CHEMBL707065
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 Synonyms

2-[[(E)-octadec-9-enoyl]amino]ethyl dihydrogen phosphate
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