2-(6-METHOXY-3-OXO-2,3-DIHYDRO-1H-INDEN-1-YL)ACETIC ACID

Modify Date: 2024-01-09 21:39:04

2-(6-METHOXY-3-OXO-2,3-DIHYDRO-1H-INDEN-1-YL)ACETIC ACID Structure
2-(6-METHOXY-3-OXO-2,3-DIHYDRO-1H-INDEN-1-YL)ACETIC ACID structure
Common Name 2-(6-METHOXY-3-OXO-2,3-DIHYDRO-1H-INDEN-1-YL)ACETIC ACID
CAS Number 24467-92-3 Molecular Weight 220.22100
Density 1.286g/cm3 Boiling Point 428.7ºC at 760mmHg
Molecular Formula C12H12O4 Melting Point 139-144ºC(lit.)
MSDS Chinese USA Flash Point 170.6ºC

 Names

Name 2-(6-methoxy-3-oxo-1,2-dihydroinden-1-yl)acetic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.286g/cm3
Boiling Point 428.7ºC at 760mmHg
Melting Point 139-144ºC(lit.)
Molecular Formula C12H12O4
Molecular Weight 220.22100
Flash Point 170.6ºC
Exact Mass 220.07400
PSA 63.60000
LogP 1.83990
Vapour Pressure 4.11E-08mmHg at 25°C
Index of Refraction 1.569

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NK8225760
CHEMICAL NAME :
1H-Indene-1-acetic acid, 2,3-dihydro-6-methoxy-3-oxo-
CAS REGISTRY NUMBER :
24467-92-3
BEILSTEIN REFERENCE NO. :
2118149
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H12-O4
MOLECULAR WEIGHT :
220.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJPPAZ Indian Journal of Physiology and Pharmacology. (All India Institute of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029, India) V.1- 1957- Volume(issue)/page/year: 24,310,1980

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS NK8225760
HS Code 2918990090

 Synthetic Route

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2-(6-METHOXY-3-OXO-2,3-DIHYDRO-1H-INDEN-1-YL)ACETIC ACID Structure

2-(6-METHOXY-3-...

CAS#:24467-92-3

Literature: Journal of the Chemical Society, , p. 3177,3179

~%

2-(6-METHOXY-3-OXO-2,3-DIHYDRO-1H-INDEN-1-YL)ACETIC ACID Structure

2-(6-METHOXY-3-...

CAS#:24467-92-3

Literature: Journal of the Indian Chemical Society, , vol. 74, # 9 p. 734 - 735

~%

2-(6-METHOXY-3-OXO-2,3-DIHYDRO-1H-INDEN-1-YL)ACETIC ACID Structure

2-(6-METHOXY-3-...

CAS#:24467-92-3

Literature: Journal of the Chemical Society, , p. 3177,3179

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles1

More Articles
Selective inhibition of the chymotrypsin-like activity of the 20S proteasome by 5-methoxy-1-indanone dipeptide benzamides.

Bioorg. Med. Chem. Lett. 8(3) , 209-14, (1998)

Potent inhibitors of the 20S proteasome that contain a novel indanone head group coupled to di and tripeptides are described. These compounds are the first proteasome inhibitors have demonstrated high...

 Synonyms

(6-Methoxy-3-oxo-indan-1-yl)-essigsaeure
1H-Indene-1-acetic acid,2,3-dihydro-6-methoxy-3-oxo
6-Methoxy-3-oxo-1-indanacetic acid
2-(6-methoxy-3-oxo-2,3-dihydro-1H-inden-1-yl)ethanoic acid
(6-methoxy-3-oxo-indan-1-yl)-acetic acid
MFCD00003787
6-Methoxy-3-oxo-2,3-dihydro-1H-indene-1-acetic acid
2-(6-methoxy-3-oxo-2,3-dihydro-1H-inden-1-yl)acetic acid
5-Methoxy-1-indanone-3-acetic acid
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