ND-011992
Modify Date: 2025-08-27 12:05:05
ND-011992 structure
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Common Name | ND-011992 | ||
|---|---|---|---|---|
| CAS Number | 2446880-46-0 | Molecular Weight | 381.35 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H14F3N3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ND-011992ND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. ND-011992 inhibits respiratory complex I and bo3 oxidase in addition to bd-I and bd-II oxidases in E. coli strain BL21*Δcyo with the IC50 of 0.12, 2.47, 0.63 and 1.3 μM, respectively. ND-011992 can be used for tuberculosis study[1]. |
| Name | ND-011992 |
|---|
| Description | ND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. ND-011992 inhibits respiratory complex I and bo3 oxidase in addition to bd-I and bd-II oxidases in E. coli strain BL21*Δcyo with the IC50 of 0.12, 2.47, 0.63 and 1.3 μM, respectively. ND-011992 can be used for tuberculosis study[1]. |
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| Related Catalog | |
| Target |
0.12 μM (respiratory complex I), 2.47 (bo3 oxidase), 0.63 (bd-I oxidases), 1.3 (bd-II oxidases) |
| References |
| Molecular Formula | C21H14F3N3O |
|---|---|
| Molecular Weight | 381.35 |
| InChIKey | CAIODVXPWNFDFE-UHFFFAOYSA-N |
| SMILES | FC(F)(F)c1ccc(Oc2ccc(Nc3ncnc4ccccc34)cc2)cc1 |