Ozenoxacin

Modify Date: 2024-01-03 10:50:29

Ozenoxacin Structure
Ozenoxacin structure
Common Name Ozenoxacin
CAS Number 245765-41-7 Molecular Weight 363.410
Density 1.4±0.1 g/cm3 Boiling Point 573.5±50.0 °C at 760 mmHg
Molecular Formula C21H21N3O3 Melting Point N/A
MSDS N/A Flash Point 300.7±30.1 °C

 Use of Ozenoxacin


Ozenoxacin is a nonfluorinated quinolone antibacterial, which shows potent activities against the main microorganisms isolated from skin and soft tissue infections.

 Names

Name 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)pyridin-3-yl]-4-oxoquinoline-3-carboxylic acid
Synonym More Synonyms

 Ozenoxacin Biological Activity

Description Ozenoxacin is a nonfluorinated quinolone antibacterial, which shows potent activities against the main microorganisms isolated from skin and soft tissue infections.
Related Catalog
Target

Bacterial[1]

In Vitro Ozenoxacin (OZN) shows potent antibacterial activities against clinical isolates of Gram-positive microorganisms, with MICs ranging from 0.008 to 4 mg/L. Ozenoxacin shows good activities against strains of MRSA, MSSA, MSSE, and MRSE with 2, 3, or 4 mutations in the gyrA and grlA (parC) genes[1]. Ozenoxacin inhibits MSSA strains and S. agalactiae strains, with the rates of resistance of >10−10 and 5.3 × 10−10, respectively. The maximum MIC value for mutant strains is 8 mg/L for ozenoxacin[2].
References

[1]. López Y, et al. In vitro activity of Ozenoxacin against quinolone-susceptible and quinolone-resistant gram-positive bacteria. Antimicrob Agents Chemother. 2013 Dec;57(12):6389-92.

[2]. López Y, et al. In vitro selection of mutants resistant to ozenoxacin compared with levofloxacin and ciprofloxacin in Gram-positive cocci. J Antimicrob Chemother. 2015 Jan;70(1):57-61

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 573.5±50.0 °C at 760 mmHg
Molecular Formula C21H21N3O3
Molecular Weight 363.410
Flash Point 300.7±30.1 °C
Exact Mass 363.158295
PSA 87.45000
LogP 3.41
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.694
Storage condition 2-8℃

 Synonyms

T 3912
UNII-V0LH498RFO
1-Cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridinyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
Ozenoxacin (JAN/INN)
3-Quinolinecarboxylic acid, 1-cyclopropyl-1,4-dihydro-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridinyl]-4-oxo-
ozenoxacin
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  • DC Chemicals Limited
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  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
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