Antitrypanosomal agent 7 structure
|
Common Name | Antitrypanosomal agent 7 | ||
---|---|---|---|---|
CAS Number | 2492436-38-9 | Molecular Weight | 480.43 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C23H31Cl2N5O2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Antitrypanosomal agent 7Antitrypanosomal agent 7 (compound 18c) is a potent and antitrypanosomal agent with favorable ADME properties. Antitrypanosomal agent 7 is > 2-fold more potent against Trypanosoma brucei (T. brucei) than Nifurtimox, with an IC50 value of 0.71 μM. Antitrypanosomal agent 7 has strong interaction to DNA and can bind with high selectivity to AT-rich DNA[1]. |
Name | Antitrypanosomal agent 7 |
---|
Description | Antitrypanosomal agent 7 (compound 18c) is a potent and antitrypanosomal agent with favorable ADME properties. Antitrypanosomal agent 7 is > 2-fold more potent against Trypanosoma brucei (T. brucei) than Nifurtimox, with an IC50 value of 0.71 μM. Antitrypanosomal agent 7 has strong interaction to DNA and can bind with high selectivity to AT-rich DNA[1]. |
---|---|
Related Catalog | |
Target |
IC50: 0.71 μM (T. brucei)[1] |
References |
Molecular Formula | C23H31Cl2N5O2 |
---|---|
Molecular Weight | 480.43 |