all-cis-4,7,10,13,16-Docosapentaenoic acid, C22:5n6
all-cis-4,7,10,13,16-Docosapentaenoic acid, C22:5n6 structure
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Common Name | all-cis-4,7,10,13,16-Docosapentaenoic acid, C22:5n6 | ||
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| CAS Number | 25182-74-5 | Molecular Weight | 330.50400 | |
| Density | 0.932g/cm3 | Boiling Point | 443.8ºC at 760mmHg | |
| Molecular Formula | C22H34O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 340.5ºC | |
Use of all-cis-4,7,10,13,16-Docosapentaenoic acid, C22:5n6Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma. |
| Name | (4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoic acid |
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| Synonym | More Synonyms |
| Description | Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma. |
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| Related Catalog |
| Density | 0.932g/cm3 |
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| Boiling Point | 443.8ºC at 760mmHg |
| Molecular Formula | C22H34O2 |
| Molecular Weight | 330.50400 |
| Flash Point | 340.5ºC |
| Exact Mass | 330.25600 |
| PSA | 37.30000 |
| LogP | 6.77290 |
| Vapour Pressure | 4.08E-09mmHg at 25°C |
| Index of Refraction | 1.509 |
| Storage condition | −20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Functional characterization of the duck and turkey fatty acyl elongase enzymes ELOVL5 and ELOVL2.
J. Nutr. 144(8) , 1234-9, (2014) In most Western countries, the consumption of fish is low and insufficient to provide the recommended daily intake of the n-3 (ω-3) long-chain polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid... |
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Docosapentaenoic acid (DPA) is a critical determinant of cubic membrane formation in amoeba Chaos mitochondria.
FASEB J. 23(9) , 2866-71, (2009) Very long-chain polyunsaturated fatty acids (VLC-PUFAs), such as docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA), have recently made it to the realm of "magical molecules" based on their mu... |
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Reevaluation of the pathway for the metabolism of 7,10,13, 16-docosatetraenoic acid to 4,7,10,13,16-docosapentaenoic acid in rat liver.
Arch. Biochem. Biophys. 317(1) , 179-84, (1995) When rat liver microsomes were incubated with [1-14C]22:4(n-6) under standard conditions for measuring acyl-CoA desaturases, it was not possible to detect the synthesis of any 22:5(n-6). When malonyl-... |
| 4Z,7Z,10Z,13Z,16Z-docosapentaenoic acid |
| all-cis-4,7,10,13,16-Docosapentaenoic acid |
| docosa-4c,7c,10c,13c,16c-pentaenoic acid |
| Osbond acid |
| C22:5n-6,9,12,15,18 |
| Docosapentaenoate |
| cis-4,7,10,13,16-docosapentaenoic acid |
| docosapentaenoic acid |