(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate

Modify Date: 2024-01-11 17:13:23

(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate Structure
(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate structure
Common Name (2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate
CAS Number 254881-77-1 Molecular Weight 244.288
Density 1.2±0.1 g/cm3 Boiling Point 370.2±42.0 °C at 760 mmHg
Molecular Formula C11H20N2O4 Melting Point N/A
MSDS N/A Flash Point 177.7±27.9 °C

 Names

Name Methyl (2R,4S)-4-aminopyrrolidine-2-carboxylate, N1-BOC protected
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 370.2±42.0 °C at 760 mmHg
Molecular Formula C11H20N2O4
Molecular Weight 244.288
Flash Point 177.7±27.9 °C
Exact Mass 244.142303
PSA 81.86000
LogP 0.18
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.507

 Synthetic Route

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(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate Structure

(2R,4S)-1-tert-...

CAS#:254881-77-1

Literature: Journal of Medicinal Chemistry, , vol. 43, # 26 p. 4948 - 4963

~%

(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate Structure

(2R,4S)-1-tert-...

CAS#:254881-77-1

Literature: Journal of Medicinal Chemistry, , vol. 43, # 26 p. 4948 - 4963

~%

(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate Structure

(2R,4S)-1-tert-...

CAS#:254881-77-1

Literature: Tetrahedron, , vol. 52, # 47 p. 15017 - 15030

~61%

(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate Structure

(2R,4S)-1-tert-...

CAS#:254881-77-1

Literature: Natchus; Bookland; De; Almstead; Pikul; Janusz; Heitmeyer; Hookfin; Hsieh; Dowty; Dietsch; Patel; Garver; Gu; Pokross; Mieling; Baker; Foltz; Peng; Bornes; Strojnowski; Taiwo Journal of Medicinal Chemistry, 2000 , vol. 43, # 26 p. 4948 - 4963

~%

(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate Structure

(2R,4S)-1-tert-...

CAS#:254881-77-1

Literature: Journal of Medicinal Chemistry, , vol. 43, # 26 p. 4948 - 4963

~%

(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate Structure

(2R,4S)-1-tert-...

CAS#:254881-77-1

Literature: Journal of Medicinal Chemistry, , vol. 43, # 26 p. 4948 - 4963

 Synonyms

(4S)-4-Amino-1-(tert-butoxycarbonyl)-2-methyl-D-proline
1,2-Pyrrolidinedicarboxylic acid, 4-amino-2-methyl-, 1-(1,1-dimethylethyl) ester, (2R,4S)-
N-a-butoxycarbonyl-trans-4-amino-L-prolinemethyl ester
(4S)-4-Amino-2-methyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-proline
2-Methyl 1-(2-methyl-2-propanyl) (2R,4S)-4-amino-1,2-pyrrolidinedicarboxylate
trans-4-amino-N-tert-butoxycarbonyl-D-proline methyl ester
1,2-Pyrrolidinedicarboxylic acid, 4-amino-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4S)-
(2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate
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