Iseganan
Modify Date: 2024-01-12 13:16:11
Iseganan structure
|
Common Name | Iseganan | ||
|---|---|---|---|---|
| CAS Number | 257277-05-7 | Molecular Weight | 1900.285 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C78H126N30O18S4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of IsegananIseganan is an antimicrobial peptide, shows broad-spectrum anti-bacteria and fungi activity. Iseganan can be used in oral mucositis research[1][2][3]. |
| Name | iseganan |
|---|---|
| Synonym | More Synonyms |
| Description | Iseganan is an antimicrobial peptide, shows broad-spectrum anti-bacteria and fungi activity. Iseganan can be used in oral mucositis research[1][2][3]. |
|---|---|
| Related Catalog | |
| In Vitro | Iseganan (200 and 400 μg/mL; 24 h) disrupts T. crassiceps cysticerci in vitro[3]. Cell Viability Assay[3] Cell Line: Cysticerci Concentration: 200 and 400 μg/mL Incubation Time: 24 hours Result: Showed loss of motility, size decreasement, as well as disruption of the bladder wall. |
| In Vivo | Iseganan (intraperitoneal injection; 200 and 400 μg per mouse; once) shows anti-parasite activity in T. crassiceps murine cysticercosis model[3]. Animal Model: Female BALB/cAnN mice injected with T. crassiceps[3] Dosage: 200 and 400 μg per mouse Administration: Intraperitoneal injection; 200 and 400 μg per mouse; once Result: Reduced the parasite load by 25% when compared with the control group. |
| References |
[1]. Toney JH. Iseganan (IntraBiotics pharmaceuticals). Curr Opin Investig Drugs. 2002 Feb;3(2):225-8. |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C78H126N30O18S4 |
| Molecular Weight | 1900.285 |
| Exact Mass | 1898.874878 |
| LogP | -4.99 |
| Index of Refraction | 1.705 |
| L-Leucinamide, L-arginylglycylglycyl-N-[(1R,4S,7R,12R,15S,18R,21S,24S,30S)-12-[(3S,9S)-14-amino-9-(aminocarbonyl)-14-imino-3-(1-methylethyl)-1,4,7-trioxo-2,5,8,13-tetraazatetradec-1-yl]-24,30-bis[3-[(aminoiminomethyl)amino]propyl]-4-[(4-hydroxyphenyl)methyl]-15-(1-methylethyl)-3,6,14,17,20,23,26,29,32-nonaoxo-21-(phenylmethyl)-9,10,34,35-tetrathia-2,5,13,16,19,22,25,28,31-nonaazabicyclo[16.14.4]hexatriacont-7-yl]- |
| L-Arginylglycylglycyl-N-[(1R,4S,7R,12R,15S,18R,21S,24S,30S)-12-({(2S)-1-[(2-{[(2S)-1-amino-5-carbamimidamido-1-oxo-2-pentanyl]amino}-2-oxoethyl)amino]-3-methyl-1-oxo-2-butanyl}carbamoyl)-21-benzyl-24,30-bis(3-carbamimidamidopropyl)-4-(4-hydroxybenzyl)-15-isopropyl-3,6,14,17,20,23,26,29,32-nonaoxo-9,10,34,35-tetrathia-2,5,13,16,19,22,25,28,31-nonaazabicyclo[16.14.4]hexatriacont-7-yl]-L-leucinamide |
| iseganan |
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Iseganan
- Price: $Inquiry/1kg
- Purity: 99.0%
- Stocking Period: 1 Day
- Contact: Vinnie
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