ND1-YL2

Modify Date: 2024-09-21 17:26:43

ND1-YL2 Structure
ND1-YL2 structure
Common Name ND1-YL2
CAS Number 2582803-80-1 Molecular Weight 2385.88
Density N/A Boiling Point N/A
Molecular Formula C114H189N27O28 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ND1-YL2


ND1-YL2 is a PROTAC that selectively degrades SRC-1 via the N-degron pathway. ND1-YL2 significantly inhibits cancer invasion and migration in vitro and in vivo. ND1-YL2 can be used in cancer research[1].

 Names

Name ND1-YL2

 ND1-YL2 Biological Activity

Description ND1-YL2 is a PROTAC that selectively degrades SRC-1 via the N-degron pathway. ND1-YL2 significantly inhibits cancer invasion and migration in vitro and in vivo. ND1-YL2 can be used in cancer research[1].
Related Catalog
Target

SRC-1[1].

References

[1]. Lee Y, et al. Targeted Degradation of Transcription Coactivator SRC-1 through the N-Degron Pathway. Angew Chem Int Ed Engl. 2020 Sep 28;59(40):17548-17555.  

 Chemical & Physical Properties

Molecular Formula C114H189N27O28
Molecular Weight 2385.88