Enfumafungin
Modify Date: 2024-01-04 13:04:10
Enfumafungin structure
|
Common Name | Enfumafungin | ||
|---|---|---|---|---|
| CAS Number | 260979-95-1 | Molecular Weight | 708.88 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C38H60O12 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EnfumafunginEnfumafungin, a triterpene glycoside, is isolated from extracts derived from an endophytic species of Hormonema. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis[1][2]. |
| Name | Enfumafungin |
|---|
| Description | Enfumafungin, a triterpene glycoside, is isolated from extracts derived from an endophytic species of Hormonema. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis[1][2]. |
|---|---|
| Related Catalog | |
| Target |
(1,3)-beta-D-glucan synthase[1] |
| In Vitro | Enfumafungin (24-48 h) has MICs of less than 0.5 μg/mL against the Candida and Aspergillus species tested and it is inactive against Cryptococcus, including the decapsulated form (MY2062)[1]. |
| In Vivo | Enfumafungin (50-200 mg/kg; i.p. twice daily for 2 days) produces a significant decrease in the number of c.f.u. in kidneys of mice challenged with C. albicans, with an ED90 of 90 mg/kg[1]. |
| References |
| Molecular Formula | C38H60O12 |
|---|---|
| Molecular Weight | 708.88 |
| Hazard Codes | Xi |
|---|
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Enfumafungin
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: Enfumafungin
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: Enfumafungin
- Price: $750.0/100mg $1200.0/250mg $2300.0/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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Price: ￥2200/5 mg
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