warfarin-potassium

Modify Date: 2024-01-01 23:52:19

warfarin-potassium structure	Common Name	warfarin-potassium
	CAS Number	2610-86-8	Molecular Weight	308.32800
	Density	1.307g/cm3	Boiling Point	515.2ºC at 760mmHg
	Molecular Formula	C₁₉H₁₆O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	188.8ºC

Name	warfarin-potassium
Synonym	More Synonyms

Density	1.307g/cm3
Boiling Point	515.2ºC at 760mmHg
Molecular Formula	C₁₉H₁₆O₄
Molecular Weight	308.32800
Flash Point	188.8ºC
Exact Mass	308.10500
PSA	67.51000
LogP	3.60960

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GN4600000

CHEMICAL NAME :: Coumarin, 3-(alpha-acetonylbenzyl)-4-hydroxy-, potassium salt

CAS REGISTRY NUMBER :: 2610-86-8

LAST UPDATED :: 199701

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C19-H15-O4.K

MOLECULAR WEIGHT :: 346.44

WISWESSER LINE NOTATION :: T66 BOVJ DYR&1V1 EO &-KA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 58 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 186 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 760 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 232 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,918,1982

RIDADR	UN 2811
Packaging Group	II
Hazard Class	6.1(a)
HS Code	2932999099

Warfarin

CAS#:81-81-2

~79%

warfarin-potassium

CAS#:2610-86-8

Literature: APOTEX PHARMACHEM INC.; BODHURI, Prabhudas; WEERATUNGA, Gamini; MURTHY, Keshava, K.S. Patent: WO2011/143747 A1, 2011 ; Location in patent: Page/Page column 15 ;

Precursor 1
CAS#:81-81-2 Warfarin
DownStream 0

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Warfarin-potassium [ISO]

Antrombin K

Athrombin-K

Warfarin K

4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one potassium salt

Potassium warfarin

potassium,2-oxo-3-(3-oxo-1-phenylbutyl)chromen-4-olate

monopotassium (RS)-2-oxo-3-(3-oxo-1-phenylbutyl)-chromen-4-olate

rac-potassium 2-oxo-3-[(1R)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-4-olate

potassium 2-oxo-3-[(RS)-3-oxo-1-phenylbutyl]-2H-chromen-4-olate

warfarin potassium

warfarin-potassium

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

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